摘要
目的评价培氟沙星治疗细菌性下呼吸道感染的临床疗效与安全性。方法将98例下呼吸道细菌感染患者随机分为2组,对照组(43例)以头孢哌酮钠-舒巴坦钠注射剂2.0g静脉滴注,每日2次;试验组(55例)给予甲磺酸培氟沙星注射剂0.4g,静脉滴注,每日2次,疗程均为7～10d。结果试验组和对照组的痊愈率分别为70.91%和72.09%,有效率分别为96.36%和93.02%;细菌清除率分别为96.55%和88.46%;不良反应发生率分别为5.45%和4.65%,两组间的差异均无统计学意义(P>0.05)。结论培氟沙星治疗常见的致病菌引起的下呼吸道感染,疗效确切,使用安全,为临床医师治疗下呼吸道感染时增加一种方法的选择,值得临床推广应用。
Objective To evaluate the efficacy and safety of Pefloxacin mesylate treating with lower respiratory infections.Method 98 cases of lower respiratory infections were divided into 2 groups.The control group（43 cases）received intravehous dripping with Cefoperazone-sulbactam 2.0g;The test group（55 cases）received intravenous dripping with Pefloxacin mesylate 0.4g.The course of treatment was 7~10 days.Results The cure rates of test groups and the control groups were 70.91% and 72.09% respectively,and the effective rates were 96.36% and 93.02% respectively;The clearance rates of bacteria were 96.55% and 88.46% respectively;The adverse reaction rates were 5.45% and 4.65% respectively.The two groups showed no significant difference（P0.05）.Conclusion The pefloxacin has good efficacy and safety for the treatment of common lower respiratory infections caused by pathogens.Therefore,it is worthy of clinical popularization.
出处
《保健医学研究与实践》
2010年第4期39-41,共3页
Health Medicine Research and Practice
