摘要
目的探讨术前碘染色在食管癌病变范围诊断中的作用及其在防止食管癌术后复发中的价值。方法对160例内镜下形态学符合食管癌的患者进行食管碘染色,并在不染区的上下端和病灶区分别取组织进行病理学检查,同时记录好染色前后病变范围的变化及有无同时存在的不染灶及病理学结果。对确诊病例进行术后追踪复查,总结存活5年以上食管癌患者的复发率。结果碘染色后98例病变范围有不同程度扩大,其中62例明显扩大,且36例存在双位或多位不染区,病理学证实为鳞癌或重度非典型增生;61例完成5年随访复查的患者无一例复发。结论对内镜下形态学符合食管癌的患者进行碘染色,对进展期食管癌病变范围的诊断和防止术后复发癌的发生有重要意义。
Objective To explore the effect of iodine staining on the diagnosis of esophageal carcinoma and its importance to prevent postoperative recurrence of esophageal carcinoma.Methods We stained the esophagus of 160 patients with esophageal carcinoma,whose esophagus had morphous coincidence with esophageal carcinoma under endoscope.After carrying out the biopsy and pathology examination of the upper and inferior extremities of nonstaining district and focal zone respectively,we recorded the variance of the extent of disease before and after staining,whether or not there were simultaneous nonstaining zones,and the results of pathology examination.We followed up and rechecked the definite diagnosed patients after the operation of esophageal carcinoma,and summarized the esophageal carcinoma recurrence rate of the cases that survived for over five years.Results After iodine staining,we found out that the extent of disease of 98 cases enlarged to different extent,included 62 cases enlarged obviously and 36 cases had double or multitudinous nonstaining zones that were confirmed carcinoma by pathology.Through summarizing and completing,we found out that there was none recurrence of 61 cases by five years'rechecking.Conclusion To carry out iodine staining on the patients with esophagus has important clinical application value on not only diagnosing the extent of disease of the progressive esophageal carcinoma but also preventing the esophageal carcinoma patients from recurring carcinoma after operation.
出处
《肿瘤基础与临床》
2010年第4期344-345,共2页
journal of basic and clinical oncology
关键词
术前碘染色
食管癌
病变范围
复发癌
iodine staining
esophageal carcinoma
the extent of disease
recurrent carcinoma