摘要
以生物医用球形雾化钛粉为原料,碳酸氢铵做造孔剂,采用放电等离子烧结(SPS)技术制备了生物医用多孔钛块体材料。采用XRD、SEM分别对所制备的多孔钛的物相组成、微观形貌进行分析,并研究了多孔钛的力学性能及成骨细胞在其表面的粘附生长情况。结果表明:通过调节造孔剂添加量、控制烧结工艺可制备孔隙率为50.3%～70.5%、孔径为100～300μm的多孔钛,其力学性能(抗压强度为24.40～68.96MPa、弹性模量为1.010～1.287GPa)与人体松质骨相匹配。与SD大鼠成骨细胞的联合培养结果表明,该材料的粗糙表面和多孔结构可粘附生长成骨细胞,具有良好的生物相容性。
Porous titanium for biomedical applications was prepared by spark plasma sintering（SPS） technology,using atomized pure titanium powders as raw material and ammonium bicarbonate as space holder.Its phase composition and micro-morphology were analyzed by XRD and SEM,respectively.Mechanical properties and biocompatibility were also investigated.By adjusting the content of space holder and controlling process parameters,specimens can be obtained with porosities in the range of 50.3%～70.5% and pore diameters in the range of 100～300μm,whose compressive strength（24.40～68.96MPa） and elastic modulus（1.010～1.287GPa） are similar to those of human cancellous bone.Rat osteoblasts can adhere to rough surface and grow into porous structure after co-cultured with porous titanium discs in vitro for 2 days,indicating that such material has good biocompatibility.
出处
《功能材料与器件学报》
CAS
CSCD
北大核心
2010年第5期490-494,共5页
Journal of Functional Materials and Devices
基金
四川省科技厅科技支撑计划资助项目(2009SZ0010)
成都市科技攻关计划资助项目(09GGZD249SF-012)
