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白细胞介素6在早产胎膜早破孕妇血清及胎膜组织中的表达 被引量:12

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摘要 目的探讨白细胞介素6(IL6)在早产胎膜早破孕妇血清中的水平及其在胎膜组织中的表达与早产胎膜早破的关系。方法采用酶联免疫吸附法和免疫组化方法,对30例早产胎膜早破孕妇(14例为早产1组,即有中、重度绒毛膜羊膜炎者;16例为早产2组,即无中、重度绒毛膜羊膜炎者)和20例正常孕妇(对照组)血清中IL6水平及胎膜组织中IL6蛋白表达进行检测。结果早产1组孕妇血清中IL6水平明显高于其他两组,差异均有极显著性(P<0.01);早产1组、早产2组及对照组IL6分别为155.17ng/L、79.11ng/L及70.15ng/L。早产两组的胎膜组织中,有绒毛膜羊膜炎者,在绒毛膜层有较多的IL6蛋白表达,在侵入绒毛膜的炎性细胞胞浆中,IL6表达更明显。结论IL6与感染引起的早产有关。
出处 《中华妇产科杂志》 CAS CSCD 北大核心 1999年第3期138-139,共2页 Chinese Journal of Obstetrics and Gynecology
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  • 1陈忠年,妇产科病理学,1996年,341页

同被引文献42

  • 1赵晓利,马晓星,孙晓明,杨道理,尹格平,陈诵芬,孙少莉.血清IL-6和IL-8对胎膜早破并发绒毛膜羊膜炎的监测[J].中华围产医学杂志,1998,1(3):135-137. 被引量:3
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