摘要
目的探讨孕激素对子宫平滑肌瘤生长的影响。方法对１３２例子宫平滑肌瘤标本的组织切片进行分析，观察每１００个高倍视野中核分裂数目与增生期和分泌期以及与患者年龄的关系。结果发现孕激素水平最高时的分泌晚期核分裂数（５９／１００ＨＰＦ）明显高于增生期（１８／１００ＨＰＦ，Ｐ＜００１），分泌期核分裂数青年组明显高于老年组（Ｐ＜００１）。结论表明孕激素是子宫平滑肌瘤的促生长因素之一。
Objective\ To investigate the effect of progesterone on the development of the uterine leiomyoma.Methods\ 132 specimens of uterine leiomyoma were studied by using histological methods.The number of nucleus division in 100HPF and its relation to proliferative phase,secretory phase,and the age of the patients were observed.Results\ We discovered that the number of nucleus division in the late secretory phase with the highest level of progesterone(5 9/100HPF)was significantly higher than that in the proliferative phase(1 8/100HPF, P <0 01).The number of nucleus division in the secretory phase of the youth group is significantly higher than that in the aged group( P <0 01).Conclusions\ These findings suggested that progesterone is one of the promoting factor for the uterine leiomyoma development.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
1999年第4期217-218,共2页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
核分裂
孕激素
子宫平滑肌瘤
Uterine leiomyoma\ Nucleus division\ Progesterone\ Secretory phase\ Proliferative phase
