摘要
对９０例脑梗塞和９０例脑溢血患者以及１０７例对照者的血脂、脂蛋白和载脂蛋白水平进行测定。结果发现脑梗塞病人ＴＣ，ＬＤＬＣ，Ｌｐ（ａ）水平较对照组高，而ＨＤＬＣ及ＡｐｏＡＩ较对照组低。脑溢血病人ＴＣ，ＬＤＬＣ及Ｌｐ（ａ）水平较对照组显著降低。多因素条件ｌｏｇｉｓｔｉｃ回归分析发现吸烟、高血压、脑卒中家族史为两型脑卒中共同危险因素，Ｌｐ（ａ）为缺血型脑卒中的独立危险因素，低ＴＣ为出血型脑卒中的独立危险因素。
The serum levels of lipids and lipoproteins were measured in 180 consecutive patients with acute stroke(90 hemorrhagic stroke, 90 ischemic stroke) and 107 age and sex matched controls. As compared with the control group, hemorrhagic group had lower levels of total cholesterol(TC)( P <0.05), low density lipoprotein cholesterol(LDL C)( P <0.01) and Lp(a)( P <0.05) while the ischemic group had higher serum TC( P <0.05), LDL C( P <0.01), Lp(a)( P <0.01) and lower high density lipoprotein cholesterol(HDL C)( P <0.05) and ApoAI( P <0.01). Multiple factor logistic regression showed that cigarette smoking, hypertension and family history of stroke were the common risk factors for both hemorrhagic and ischemic stroke, and that lowered TC and elevated Lp(a) levels were independent risk factors for hemorrhagic stroke and ischemic stroke respectively.
出处
《湖南医科大学学报》
CSCD
1999年第2期167-170,共4页
Bulletin of Hunan Medical University
关键词
中风
脂蛋白
载脂蛋白
血脂
cerebral hemorrhage
cerebral infarction
lipoprotein
factor analysis
statistics
