摘要
目的：为了观察康莱特与化疗联用对食管癌的治疗效果。方法：将９５例中晚期食管癌患者随机分入康莱特联用ＤＤＰ＋５－ＦＵ组和单纯ＤＤＰ＋５－ＦＵ化疗组。结果：１）两组有效率分别为７３％和５３％，差异显著（Ｐ＜０．０５），前者的完全缓解率也较高；２）联用组治疗前后ＫＰＳ评分改善及稳定者也明显高于单纯化疗组（Ｐ＜０．０１）；３）化疗结束后联用组有３／４患者能够及时放疗，而单纯化疗组只有不足１／２患者能按期放疗。结论：长期应用康莱特能使患者ＫＰＳ提高或保持稳定。有助于提高疗效，延长缓解期。
The aim of the trial was to evaluate the curative effect of Kanlaite injection(KLT) onesophageal carcinoma. Ninety - five patients with esophageal cancer were divided into the KLT - DDP/5 - Fu combination treatment group of 44 cases and the chemotherapy alone group of sl cases. The re-sults showed that ( 1 ) The effective rate (CR + PR) in combination treatment group was 73% which wassignificantly higher than 63% of the control group (P<0. 05) . (2) The change of general condition af-ter treatment had marked difference (P< 0.01) . (3) 3/4 of cases in the combination treatment groupbegan radiotherapy immediately and more than 1/2 of the patients of control group had delayed one week.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1999年第4期296-297,共2页
Chinese Journal of Clinical Oncology
