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短期胰岛素泵强化治疗老年糖尿病62例

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摘要 目的探讨短期胰岛素泵强化治疗口服降糖药继发性失效的老年糖尿病的疗效。方法选取住院的老年糖尿病患者124例,随机分为胰岛素泵组和多次胰岛素注射组,两组患者予以短期胰岛素强化治疗,比较治疗后的血糖、糖化血红蛋白、血糖达标时间、胰岛素日用量、日内平均血糖波动幅度及治疗过程中两组的低血糖发生率。结果治疗后两组的空腹及餐后血糖均明显下降,胰岛素泵组血糖达标时间及餐后2小时血糖明显低于多次胰岛素注射组(P<0.05),而且前组胰岛素日用量显著少于后组(P<0.01),但两组间空腹血糖、日内血糖波动幅度和糖化血红蛋白比较差异无统计学意义(P>0.05)。在治疗过程中两组均有低血糖发生,但发生率无显著性差异(P>0.05)。结论短期胰岛素泵强化治疗能安全、有效地控制血糖,而且胰岛素日用量更少。
作者 王保法 傅莉萍 洪郁芝 彭春玲
机构地区 杭州市中医院
出处 《浙江实用医学》 2010年第5期368-369,共2页 Zhejiang Practical Medicine
关键词 老年糖尿病 胰岛素泵(CSⅡ) 多次胰岛素注射强化(MSⅡ)
分类号 R587.1 [医药卫生—内分泌]
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参考文献6

  • 1UK Prospective Diabetes Siudy (UKPDS) Group.Intensive bloodglucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabeles (UKPDS 33).Lancet,1998,352(9131):837.
  • 2刘石平,莫慧,刘碧莲,唐炜立,邓小戈,苏欣,姚岚,林健,冯琼,彭健,周智广,李一君.短期持续皮下胰岛素输注对新诊断2型糖尿病患者胰岛功能、胰岛素抵抗和血管内皮细胞损伤的作用及其机制[J].中华内科杂志,2010,49(5):405-409. 被引量：18
  • 3武晋晓,吕肖峰,刘福平.胰岛素泵治疗糖尿病的临床观察[J].中华内分泌代谢杂志,2005,21(3):276-277. 被引量：83
  • 4Wolff-McDonagh P,Kaufmann J,Foreman S,et al.Using insulin pump therapy in poorly controlled type 2 diabetes.Diabetes Educ,2010,36(4):657.
  • 5Bailon R M,Partlow B J.Miller-Cage V,et al.Continuous subcutaneous insulin infusion (insulin pump) therapy can be safely used in the hospital in select patients.Endocr Pract,2009,15(1):24.
  • 6Fahlén M,Eliasson B,Odén.A.Optimization of basal insulin delivery in Type 1 diabetes:a retrospective study on the use of continuous subcutaneous insulin infusion and insulin glargine.Diabet Med,2005,22(4):382.

二级参考文献21

  • 1ADVANCE Collaborative Group,Patel A,MacMahon S,et al.Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.N Engl J Med,2008,358:2560-2572.
  • 2Dackworth W,Abraira C,Moritz T,et al.Glucose control and vascular complications in veterans with type 2 diabetes.N Engl J Med,2009,360:129-139.
  • 3Action to Control Cardiovascular Risk in Diabetes Study Group,Gerstein HC,Miller ME,et al.Effects of intensive glucose lowering in type 2 diabetes.N Engl J Med,2008,358:2545-2559.
  • 4Ismail-Beigi F,Moghissi ES.Glycemia management and cardiovascular risk in type 2 diabetes:an evolving perspective.Endocr Pract,2008,14:639-643.
  • 5Holman RR,Paul SK,Bethel MA,et al.10-year follow-up of intensive glucose control in type 2 diabetes.N Engl J Med,2008,359:1577-1589.
  • 6Del Prato S,Tiengo A.The importance of first-phose insulin secretion:implications for the therapy of type 2 diabetes mellitus.Diabetes Metab Res Rev,2001,17:164-174.
  • 7Ilkova H,Glaser B,Tunckah A,et al.Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment.Diabetes Care,1997,20:1353-1356.
  • 8Weng J,Li Y,Xu W,et al.Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes:a multicentre randomised parallel-group trial.Lancet,2008,371:1753-1760.
  • 9Li Y,Xu W,Liao Z,et al.Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function.Diabetes Care,2004,27:2597-2602.
  • 10Lim HS,Chong AY,Freestone B,et al.The effect of multifactorial intervention on plasma yon Willebrand factor,soluble Eselectin and tissue factor in diabetes mellitus:implications for atherosclerotic vascular disease.Diabet Med,2005,22:249-255.

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浙江实用医学
2010年 第5期

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