摘要
目的:研究anti-TgAb和anti-TPOAb在自身免疫性甲状腺疾病中的诊断价值。方法:分析在本院乳甲科就诊的171例患者资料,分为桥本甲状腺炎(HT)组,Graves组,结节性甲状腺肿组,甲状腺腺瘤组和甲状腺乳头状瘤组。化学免疫发光分析法测定血清anti-TgAb和anti-TPOAb,40例健康体检者为正常对照。结果:HT组和Graves组anti-TgAb和anti-TPOAb均高于其他4组(P<0.05);HT组anti-TgAb大于正常值1、3倍,Graves组大于正常值1倍和两组anti-TPOAb大于正常值1、3、10倍例数均高于其他4组(P<0.05);HT组和Graves组两项都大于参考值1、3倍的数量高于其余各组(P<0.05)。而HT组和Graves组间的差异无统计学意义(P>0.05)。结论:血清anti-TgAb和anti-TPOAb测定值的增高对HT和Graves的诊断有意义。
Objective：To study the diagnosis significance of anti-TgAb and anti-TPOAb in autoimmune thyroid disease.Methods： 171 patients in hospital were separated into Hashimoto′s thyroiditis group,Graves disease group,nodulargoiter group,thyroid adenoma group and papillary thyroid carcinoma group.The anti-TgAb and anti-TPOAb level were measured by immunochemiluminometry method,and 40 cases of healthy people as control.Results： The anti-TgAb and anti-TPOAb of HT and Graves groups were higher than the other 4 groups（P0.05）.The HT patients with more than 1 and 3 folds and the Graves patients with more than 1 folds of normal Anti-TgAb value was significantly more than other groups;The number of HT and Graves patients with more than 1,3,10 folds more than normal anti-TPOAb value was also significantly more than other 4 groups（P0.05）.In HT and Graves groups,the patients whose anti-TgAb and anti-TPOAb value increased 1,3 folds simultaneously were significantly more than the other 4 groups（P0.05）.There was no obviously difference between HT and Graves group（P0.05）.Conclusion： The increase of serum anti-TgAb and anti-TPOAb value strongly suggest the diagnosis of HT and Graves.
出处
《中国卫生检验杂志》
CAS
2010年第11期2866-2867,2870,共3页
Chinese Journal of Health Laboratory Technology
