摘要
目的探讨下肢骨折患者创伤后机体的凝血状态变化及与发生血栓性疾病的关系。方法选择下肢骨折患者1958例,及其他无创伤住院患者956例,于入院后第二天早晨采集外周静脉血测定血浆凝酶原时间(PT)、国际标准化比值(INR)、活化的部分凝血活酶时间(APTT)、凝血酶时间(TT)及纤维蛋白原(Fib)。结果与对照组结果比较,下肢骨折患者创伤后PT、INR、TT、Fib差异有统计学意义。结论下肢骨折患者创伤后机体凝血系统被激活,处于高凝状态,有并发血栓形成的危险,尤其应警惕Fib的持续升高,防止血栓形成。
Objective To investigate the change of blood coagulation status in lower limp fracture patients,and to research the relations between clotting and thrombosis.MethodsThe research chose lower limb fracture patient 1958 examples and other non-wound in hospital patient 956 examples.After in hospital,each patient drew circumference venous blood to detect PT、INR、APTT、TT、Fib.ResultsCompares with the control group,the lower limb fracture had significant differences in PT、INR、TT、Fib.Conclusion The lower limb fracture patients were in hypercoagulative state and danger of thrombosis after the bone fracture.We shoud pay attention to Fib continues to elevate and prevent the thrombus to form.
出处
《四川医学》
CAS
2010年第11期1691-1692,共2页
Sichuan Medical Journal
关键词
下肢骨折
凝血
血栓
lower limb fracture
blood coagulation
thrombus
