摘要
目的评价大剂量静脉注射丙种球蛋白治疗重度新生儿缺氧缺血性脑病的效果。方法 50例重症HIE患儿随机分成治疗组和对照组,两组病例均予常规治疗,治疗组在此基础上加用静脉注射丙种球蛋白(1.0g·kg-1·d-1)。结果治疗组原始反射恢复时间、肌张力恢复时间、惊有厥停止时间、NBNA评分与对照组比较,P<0.01, 差异有统计学意思。结论大剂量静脉注射丙种球蛋白治疗重度新生儿缺氧缺血性脑病疗效显著。
Objective To evaluate the effect of large-doses injection of immunoglobulin（IVIG）in the treatment of hypox-ischemic encephalopathy（HIE）.Methods 50 cases with HIE were randomly divided into treatment group（N=18） and control group（N=32）.Two groups were received conventional treatment,while the treatment group was administrated in addition large injection of immunoglobulin（1.0 g·kg-1·d-1）） for three days.Results The recovery time of primitive reflection,the recovery time of muscular tension and NBNA in treatment group was shorter than those in the control group,and there was significantly difference in the treatment group and the control group.Conclusion Large-dose injection of immunoglobulin has a good therapeutic effect in the treatment of HIE.
出处
《海南医学》
CAS
2010年第21期89-89,145,共2页
Hainan Medical Journal
关键词
静脉注射丙种球蛋白
新生儿
缺氧缺血性脑病
Injection immunoglobulin（IVIG）
Neonatal
Hypox-ischemic Encephalopathy（HIE）
