摘要
目的比较131I与抗甲状腺药物(ATD)治疗甲亢的疗效。方法将640例甲亢患者随机分为两组,分别采用131I(310例)和ATD(330例)治疗,并随访3年,观察疗效和不良反应。结果两组的治愈率和复发率差异有统计学意义(分别为85.8%对46.7%,4.5%对39.7%,P<0.01);突眼转归比较差异无统计学意义(P>0.05);甲减发生率比较差异有统计学意义(P<0.05)。结论 131I治疗甲亢综合疗效优于抗甲亢药物。
Objective To compare the curative effect of 131I with that of anti - thyroid drugs （ATD）. Methods 640 cases with hyperthy- roidism were randomly divided into 2 groups 131I group （ n = 310） and ATD group （ n = 330 ） ; the follow - up lasted from 3 years to observe the curative effect and side effect. Results The difference in recovery rate （85.8%/46. 7 ） and re -occurrence rate （4.5%/39.7% ） between the 2 groups was of statistical significance （ P 〈 0. 01 ） ; the comparison of exophthalmos prognosis between the 2 groups was of no sta- tistical difference （P 〉 0. 05 ） ; the comparison of hypothyroidism between the 2 groups was of statistical significance. Conclusions The general curative effect of 131I in treating hyperthyroidism is superior to that of ATD.
出处
《西南军医》
2010年第6期1051-1052,共2页
Journal of Military Surgeon in Southwest China
