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TIM-3分子与临床疾病相关研究进展 被引量：2

Research Progression of TIM-3 and Correlation with Some Clinical Diseases
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摘要 TIM-3是TIMs家族中一个重要的成员,具有多种生物学作用。它是区分Th1/Th2细胞特异性的表面标志,还参与机体的固有免疫和特异性免疫应答的调节,与多种临床疾病的致病机制密切相关。本文就TIM-3的结构、表达、配体及与多种临床疾病的关系作一综述。 TIM-3 is an important member of TIMs gene family with diverse biological functions,which is not only the specific surface marker for distinguishing Th1 and Th2 cells,but also the important molecule involved in the regulation of innate immune response and adaptive immune response.TIM-3 is also connected tightly with pathogenesis of some clinical diseases.Here we have a review on the structure,expression,ligands of TIM-3 and correlation with some clinical diseases.
作者 马德强 郝友华 杨东亮
机构地区 华中科技大学同济医学院附属同济医院临床免疫研究室 郧阳医学院附属太和医院感染科
出处 《免疫学杂志》 CAS CSCD 北大核心 2010年第11期996-999,共4页 Immunological Journal
基金 国家自然科学基金(30400412)
关键词 TIM-3分子 临床疾病 TIM-3 Clinical diseases
分类号 R392.3 [医药卫生—免疫学]
  • 相关文献

参考文献24

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二级参考文献24

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共引文献19

同被引文献15

  • 1张才成,吴健民,崔天盆,王平,潘世秀.湖北汉族人群TIM-3基因多态性与变应性哮喘的相关性[J].中华医学遗传学杂志,2006,23(1):74-77. 被引量：24
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引证文献2

二级引证文献7

免疫学杂志
2010年 第11期

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