摘要
目的从天人相应理论入手探讨冬夏季节对人体细胞免疫功能的影响。方法对20例大学生志愿者分别在立夏(SB)、夏至(SS)、立冬(WB)、冬至(WS)实验日采用不同方法检测免疫物质水平,每次所测分为立夏组、夏至组、立冬组、冬至组。应用流式细胞术对健康人血清中淋巴细胞免疫标志CD3+、CD4+、CD8+、CD56+进行分析。结果立夏组、夏至组健康人外周血T淋巴细胞CD3+、CD4+、CD4+/CD8+均不同程度显著高于立冬组、冬至组。冬夏季节各组对T淋巴细胞CD8+和NK细胞CD56+无明显影响。结论冬夏季节对机体细胞免疫功能具有一定的调节作用,免疫功能存在夏季强冬季弱的变化趋势,与中医天人相应和肺卫防御理论的认识是一致的。
Objective To study the influences of seasonal changes of winter and summer on human peripheral blood immune lymphocytes based on the theory of correspondence between nature and human.Methods The levels of immune substance were detected with different methods respectively at the Summer Beginning（SB）,Summer Solstice（SS）,Winter Beginning（WB） an Winter Solstice（WS） in 20 college volunteers.The outcomes were then divided into the SB group,SS group,WB group and WS group.The serum content of lymphocyte immunological markers（CD3＋,CD4＋,CD8＋ and CD56＋） were analysed by using flow cytometry.Results The content of CD3＋,CD4＋,and the ratio of CD4＋ to CD8＋（CD4＋/CD8＋） were higher significantly in the SB group and SS group than those in the WB group and WS group in varying degrees.The seasons of summer or winter had no significant influence on CD8＋ in T cells and CD56＋ in natural killer cells（NK）.Conclusion Winter or summer had some regulation actions on body＇s immunity.The immunity tends to strong in summer and poor in winter,which accords with TCM theory of correspondence between nature and human,and defense function of lung and defense aspect.
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2010年第2期106-109,共4页
Journal of Beijing University of Traditional Chinese Medicine
基金
国家中医药管理局科研基金资助项目(No.06-07JP09)
关键词
冬夏季节
T淋巴细胞
NK细胞
免疫功能
天人相应
健康人
winter and summer
T lymphocyte
natural killer cells
immune function
correspondence between nature and human
health person
