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布托啡诺联合吗啡用于剖宫产术后镇痛的临床观察 被引量:4

CLINICAL OBSERVATION OF THE POST - OPERATIVE ANALGESIA EFFECT OF BUTORFANOL ASSOCIATED WITH MORPHINE FOR CESARIAN SECTION
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摘要 目的比较吗啡和布托啡诺联合吗啡用于剖宫产术后镇痛的效果及副作用,探讨术后硬膜外镇痛用药的最佳配伍。方法 60例ASAⅠ或Ⅱ级在腰硬联合麻醉下行剖宫产手术术后行硬膜外镇痛,依据硬膜外用药不同随机分组:B组为观察组,首量用布托啡诺1 mg+吗啡2 mg+0.2%罗哌卡因+生理盐水共6 ml注入硬膜外,维持用药布托啡诺4 mg+吗啡5 mg+0.2%罗哌卡因+生理盐水共100 ml;M组为对照组首量用吗啡2 mg+0.2%罗哌卡因+生理盐水共6 ml注入硬膜外,维持用药:吗啡8 mg+0.2%罗哌卡因+生理盐水共100 ml;观察患者术后6、12、24、48 h各个时间段的视觉模拟镇痛评分(VAS)、Ramsay镇静评分、BCS舒适评分,是否出现皮肤瘙痒、恶心呕吐(PONV)以及是否出现低血压及呼吸抑制等其他不良反应。结果 B组和M组在术后各时间段镇痛镇静舒适度评分无显著性差异,B组不良反应瘙痒、恶心呕吐发生率明显下降,与M组有显著性差异。结论布托啡诺联合吗啡用于剖宫产术后镇痛效果满意,不良反应少,是一种较好的术后镇痛用药方案。
出处 《现代医院》 2010年第11期36-37,共2页 Modern Hospitals
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  • 1RCIHARD A,JAFFE,STANLEY I.Samuels.陈宁,韩建阁,译.斯坦福临床麻醉全书[M].3版.天津:天津科技翻译出版公司,2005:144-148.
  • 2WHITESIDE R,JONE D,BIGNELL S,et al.Epidulal ropivacane with fentanyl following majar gynaecological Surgery:the effect of volume and concentration of pain relief and motor impairment[J].Br J Anaesth,2000,84(6):720-724.
  • 3JIN F.CHUNG F.Multimodal analgesis for postoperative pain control[J].J clin Anesth,2001,13:524-539.
  • 4WANG F,SHEN X,LIU Y,et al.Continuous infusion of butorphanol combined with intravenous morphine patient-controlled analgesia after total abdominal hysterectonmy:a randomized,double-blind controlled trial[J].Eur J.Anaesthesiol,2009,26:28-34.
  • 5COMMISKEY S,FANLW,HO I K,et al.Butorphano:I effects of a prototypical agonist-antagonist analgesic on Kappa-opioid receptors[J].Pharmacol Sci,2005,98(2):109-116.
  • 6ALEXANDER J I.Pain after laparoseopy[J].Br JAnaesth,1997,79:369-378.
  • 7WANG J J,SH-WEI S P,CANKHETAL.Postoperative pain relief with various epidural narcotics:demerol,butorphanol,nalbuphine and morphine[J].Ma Zui Xue Za Zhi,1988,26(1):15-24.
  • 8王春晓.现代术后镇痛学[M].广州:广东科技出版社,2007:140-152.
  • 9张重,郭曲练,赵媛,熊云川,邹望远.硬膜外泵入布托啡诺复合小剂量氯胺酮用于妇科患者术后镇痛[J].临床麻醉学杂志,2008,24(7):577-579. 被引量:13
  • 10GAMAN W R,LOFERSKI B L,FANEIULLO G S,et al.Does epiduraladmnistration of butor-phanol offer anyclinical advantage over the intravenous route:A double-blind placeba controlled trial[J].Anesthesiology,1992,76:216-220.

二级参考文献5

  • 1胡永明,孔明健.布托啡诺用于剖宫产术后硬膜外镇痛[J].临床麻醉学杂志,2007,23(8):691-692. 被引量:15
  • 2Commiskey S,Fan LW, Ho IK,et al. Butorphanol: effects of a prototypical agonist-antagonist analgesic on kappa-opioid receptors. J Pharmacol Sci,2005, 98:109-116.
  • 3Subramaniam K,Subramaniam B,Pawar DK, et al. Evaluation of the safety and efficacy of epidural ketamine combined with morphine for postoperative analgesia after major upper abdominal surgery.J Clin Anesth, 2001,13: 339-344.
  • 4Subramaniam K, Subramaninam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg, 2004,99 : 482-495.
  • 5Sehmid RL, Sandier AN, Katz J. Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes. Pain, 1999,82: 111- 125.

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