摘要
目的:分析桥脑外髓鞘溶解症(EPM)的MRI特点。方法:经临床及影像确诊的EPM患者10例,均行头颅MRI检查,其中2例仅行平扫,8例行平扫和增强扫描,回顾性分析其MRI表现,总结其诊断和鉴别诊断要点。结果:10例患者均出现双侧尾状核、豆状核对称性异常信号,T1WI病灶呈低信号,T2WI呈稍高信号,T2-FLAIR病灶呈更加明显的异常高信号,增强扫描无明显强化。其它病灶分布:双侧背侧丘脑2例,双侧岛叶1例,顶叶皮层下白质3例;3例患者伴发脑桥中央对称性异常信号。结论:EPM的MRI表现具有一定特征性,结合临床及实验室检查可作出正确诊断。
Objective：To analyze the MRI characteristics of extrapontine myelinolysis （EPM）. Methods： 10 cases with clinical and imaging diagnosed EPM before treatment were enrolled in this study. All patients had cerebral MRI,with 2 pa tients had plain and 8 patients had both pre and post-contrast MR1 scanning. The MRI findings were analyzed retrospectively, the characteristics for diagnosis and differential diagnosis were discussed. Results：Symmetric abnormal signal intensities on bilateral caudate and lenticular neclei were observed in all 10 cases. The lesions showed hypo-intensity on T1WI, slight hyper-intensity on T2 WI and markedly abnormal hyper-intensity on T2-FLAIR,no obvious enhancement was showed after contrast administration. Lesions could also be revealed on bilateral dorsal aspect of thalamus （n= 2）, bilateral insula （n = 1） and subcortical white matter in parietal lobe （n=3）. 3 patients had associated abnormal signal intensities in the center of pontine. Conclnsion：Extrapontine myelinolysis has characteristic MRI findings. Accurate diagnosis can be made based on MRI findings in combination with clinical manifestations.
出处
《放射学实践》
北大核心
2010年第11期1190-1193,共4页
Radiologic Practice
关键词
桥脑外髓鞘溶解症
磁共振成像
诊断
Extrapontine myelinolysis
Magnetic resonance imaging
Diagnosis
