摘要
目的探讨毛发红糠疹临床及病理改变特点。方法收集20例毛发红糠疹标本，所有标本均用4％甲醛溶液固定，常规脱水、包埋、切片、HE染色，分析总结其临床病史及病理改变特点。结果20例毛发红糠疹患者中，男性8例，女性12例，年龄最小4岁，最大65岁。临床主要表现为融合性毛囊角化过度性丘疹，镜下可见角质层垂直和水平方向交替出现角化过度和角化不全，毛囊角栓形成。结论毛发红糠疹是一种以毛囊角化为主的红宽鳞屑性皮肤疾病，组织病理检查可见特征性改变。需注意与其它疾病的鉴别诊断。
Objective To discuss the clinical opathologic features of pityriasis rubra pilaris（PRP）. Methods We collected 20 cases of PRP from 20 patients, all the specimen were fixed in 4% liquer formaldehydi. The entire specimen were serially cut, processed routinely for paraffin embedding, and stained with hematoxylin eosin stains. Analysis the clinicopathology features of PRP. Results In these 20 cases of PRP patients,there were 8 men and 12 women,ranging in age from 4 to 65 years. All cases mainly presented as confluence of hyperkeratotic papules. On magnification, there is alternative oceurrenc of hyperkeratosis and parakeratosis in level and vertical orientation of the cuticle, and follicular plugs was noted. Conclusion Pityriasis rubra pilaris is one kind of abnormality of keratinizatial process, there is characteristic exhibition on magnification and some other conditions should be considered in the differential diagnosis .
出处
《中外医学研究》
2010年第27期12-14,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
毛发红糠疹
临床病理分析
Pityriasis rubra pilaris
Clinicopathologic analysis
