摘要
本文综述了超分子环糊精两亲分子的最新研究进展。超分子环糊精两亲分子主要包括疏水性修饰的环糊精衍生物(第一类)、环糊精衍生物与两亲分子的包合物(第二类)和环糊精衍生物与疏水性客体分子的包合物(第三类)。针对超分子环糊精两亲分子及其自组装体系的研究不但丰富了由诺贝尔化学奖得主Lehn等所提出的超分子化学的内涵,实现了多学科的交叉,而且在生物模拟、智能材料以及可控的、具有疗效的药物输运与缓释等领域具有潜在的应用前景。
The recent progress in＂supramolecular cyclodextrin amphiphile＂is reviewed in this manuscript.The supramolecular cyclodextrin amphiphiles have three main types： the first class containing the cyclodextrins with hydrophobic modifications,the second class containing the inclusion complexes between cyclodextrins and amphiphiles,and the third class containing inclusion complexes between cyclodextrins and hydrophobic guests.The investigations on supramolecular cyclodextrin amphiphiles and their self-assemblies not only expand the concept of ＂supramolecular chemistry＂introduced by Lehn,the Nobel Prize winner in chemistry in 1987,but also have the potential applications to bio-mimicry,smart materials and controllable therapeutic drug delivery and release systems.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2010年第12期2276-2281,共6页
Progress in Chemistry
关键词
环糊精
超分子两亲分子
自组装
主客体作用
cyclodextrins
supramolecular amphiphiles
self-assembly
host-guest interaction
