摘要
目的分析血清抗线粒体抗体(AMA)阳性患者的实验室指标,探讨抗线粒体抗体的诊断价值。方法将AMA阳性患者63例,分为原发性胆汁性肝硬化(PBC)47例和非PBC 16例,分析每组生化、免疫学指标。结果与47例PBC患者比较,16例非PBC患者ALP、r-GT升高无PBC组明显(P<0.001)。ANA、抗dsDNA阳性率无PBC组高(P<0.01)。结论 AMA在PBC患者中检出率极高,但AMA并不只出现在PBC患者血清中。在肝胆疾病、其他疾病患者血清中亦可检出,二者实验室检查有差异。
Objective The detection index of patients with AMA seropositivity was analysed to explore the diagnostic value of AMA.Methods 63 cases with AMA seropositivity were divided into two groups,one of which（the subject group） included 47 cases with PBC,the other（the control group） involved 16 cases with non-PBC.The biochemical and immunological indexes were examined in each of the above two groups.Results Compared to the subject group,in 16 cases with non-PBC,ALP and r-GT did not rise so significantly as that of the subject group（P0.001） and the positive rate of ANA and anti-dsDNA antibodies was not as high as that of the subject group（P0.01）.Conclusions The detection rate of AMA proves to be extremely high in patients with PBC.Nevertheless,AMA is found in the serum from patients with diseases in the liver and gallbladder and from patients suffering from other diseases as well as in the serum from patients with PBC.Therefore,some difference is discovered in the lab detection of the above two indexes.
出处
《中国误诊学杂志》
CAS
2010年第35期8576-8577,共2页
Chinese Journal of Misdiagnostics
关键词
线粒体/免疫学
抗体/分析
肝硬化
胆汁性/诊断
Mitochondria/immunology
Antibodies/analysis
Liver Cirrhosis
Biliary/diagnosis
