摘要
目的:探讨艾司西酞普兰与米氮平治疗抑郁症的疗效与不良反应。方法:将68例符合CCMD-3诊断标准的抑郁症患者随机分为两组,分别给予艾司西酞普兰和米氮平治疗,疗程8周,于治疗前和治疗后1、2、4、6、8周末采用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表病情严重程度(CG I-SI)评定疗效,副反应量表(TESS)评定安全性。结果:艾司西酞普兰与米氮平对抑郁症疗效相仿,起效更快,不良反应少。结论:艾司西酞普兰是一种安全有效的抗抑郁药。
Objective：To compare the efficacy and safety of Escitalopram and Mirtazapine in the treatment of depression. Methods：68 patients with depression by CCMD -3 were randomly allocated to two groups with Escitalopram or Mirtazapine for 8 weeks. HAMD CGI - SI scale and TESS scale were used to evaluate efficacy and side effects respectively before and at the ends of 1, 2,4,6,8 weeks of treatment. Results： The total effective rates for the Escitalopram and Mirtazapine groups were similar after 8 weeks （ P 〉 0.05）. Incidence of side effects in the Escitalopram group was lower than that in the Mirtazapine group. Conclusions： The results suggest that Escitalopram is effective and safe anti -depression drug.
出处
《中国民康医学》
2010年第23期3006-3007,共2页
Medical Journal of Chinese People’s Health
