摘要
目的探讨大肠腺瘤的发生、分布、病理特点及与癌变的关系。方法对384例大肠腺瘤性息肉按性别、息肉发生部位、息肉大小、病理类型及不典型增生程度等因素进行分析。结果腺瘤性息肉发生在左半结肠的比例(74.7%)较发生在右半结肠的比例(25.3%)高;右半结肠腺瘤性息肉多见于男性(男∶女=2.9∶1),而女性腺瘤性息肉较之男性更多见于左半结肠(女∶男=2.2∶1);直肠,乙降结肠,横结肠,升结肠2cm的腺瘤性息肉分别为1.6%、6.5%、1.3%及0.5%,上述部位管状-绒毛状腺瘤性息肉分别为4.7%、10.2%、1.8%和4.4%,而绒毛状腺瘤在上述部位的比例分别为0.8%、1.6%、1.0%和0.8%,尽管重度不典型增生的腺瘤性息肉在例数上多见于直肠、乙降结肠,横结肠、升结肠次之,但不同部位腺瘤性息肉的不典型增生程度差异无统计学意义;检出的重度不典型增生性腺瘤息肉共13例,其中没有1cm以下的息肉,且2cm以上者与1～1.9cm者之比为2.25∶1,所检管状、管状-绒毛状及绒毛状重度不典型增生性腺瘤息肉之比为1∶7∶5。结论大肠腺瘤性息肉的发生存在部位、性别的差异,不同部位大肠腺瘤性息肉存在大小及病理类型的差异,息肉不典型增生程度则与息肉的大小及病理类型相关,上述特征有助于肠镜检查时对大肠息肉性质的初步判断,提高重度不典型增生性息肉的检出,从而减少大肠癌的发生。
Objective To analyze the characteristics of adenomatous polyps（AP） in large intestine.Methods 384 patients with AP were retrospectively analyzed,including gender,site,size,pathology and the degree of atypical hyperplasia.Results The incidence of AP in the left part colon（74.7%） was higher than that in the right part（25.3%）.The rate of the AP larger than 2cm occurring in rectum,sigmoid-descending colon,transverse colon and ascending colon were 1.6%,6.5%,1.3% and 0.5%,respectively.The tubular-villiform AP occurred in above-mentioned colon parts were 4.7%,10.2%,1.8% and 4.4%,respectively.The villiform AP occurring in above-mentioned colon parts were 0.8%,1.6%,1.0% and 0.8%,respectively.There was no severe atypical hyperplasia appear in AP smaller than 1cm.Conclusions The generation of AP is different in various sites and gender.There is difference of size and pathology in AP occurring in various colon parts.The degree of severe atypical hyperplasia is associated with the size and pathology of AP.
出处
《西部医学》
2010年第12期2223-2225,共3页
Medical Journal of West China
