摘要
目的：探索Tourette综合征（TS）的预后以及相关因素。方法选择6～12年前符合CCMD－2－R诊断标准的65例TS进行随访，采用耶鲁精神卫生中心的TS严重程度量表（YGTSS）和自制调查表。按YGTSS评分分为痊愈组、好转组和未愈组，分析三组的各项临床资料与预后的关系。结果青春期抽动症状痊愈好转率为90．77％，TS预后与起病年龄和治疗无显著关系，可能与神经精神病家族史和既往病史有关（0．01＜P＜0．05），与伴发其他精神疾病关系明显（P＜0．01）。TS预后对完成学业无明显影响。发声抽动与其他运动性抽动一样，在病程中交替出现。结论大部分TS患者预后良好，个别病例症状无改变且多伴重性精神病。提示我们及时控制抽动症状，减轻患者的身体不适和心理压力，可能有益于TS的预后、防止重性精神病的出现。
The aim of this study was to investigate the prognosis of TS and influence factors inprognosis. Methods 65 cases patients studied met CCMD-2-R criteria for TS and evaluated withYGTSS and a self designed questionnaires. According to YGTSS score all patient was classified threegroups: recover、better and unchange. Analysis relationship between clinical datum of three groups. Results 31 (47. 7 % ) patients were recover, 28 (43. 1 % ) were lessened and 6 (9. 2 % ) were unchange. TSprognosis had no relaied to onset old and treatment(P<0. 05), but signify to family and pass histories(0. 01 < P< 0. 05) and had higher related to follow else psychosis(P<0. 01). Patienet' studies had notaffected by TS prognosis. Noises symptom as well as other tics arise alternately in couse. ConclusionMostly prognosis of TS is better, indivedual ties are unchange and easier appear seriously psyshosis. Reminding us for lessening body trouble and mind pressure that tics arc controled timely while possible toimprove prognosis of TS and avoid other psychosis.
出处
《四川精神卫生》
1999年第2期85-87,共3页
Sichuan Mental Health
