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OXA型超广谱β-内酰胺酶的研究进展 被引量：6

Advances in study on OXA-type extended-spectrum β-lactamases
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摘要 近年来，第三代头孢菌素和氨曲南等氧亚氨基β-内酰胺类抗生素被广泛用于临床抗感染治疗，使耐药形势日趋严重，而导致细菌对此类药物耐药的最主要原因是产生超广谱β-内酰胺酶（extendedspectrum β-lactamases，ESBLs）。特别是1983年德国首次从臭鼻克雷伯菌发现产ESBLs株以来，
作者 刘晓一 刘文恩
机构地区 中南大学湘雅医院
出处 《中国感染控制杂志》 CAS 2010年第6期462-467,共6页 Chinese Journal of Infection Control
关键词 超广谱Β-内酰胺酶 OXA型 抗生素 抗药性 微生物
分类号 R969.3 [医药卫生—药理学]
  • 相关文献

参考文献22

  • 1Bert F, Branger C, Lambert Zechovsky N. Identification of PSE and OXA β-lactarnase genes in Pseudomonas aewuginosa using PCR - restriction fragment length polymorphism [J]. J Antimicrob Che mother,2002,50(1) : 11 - 18.
  • 2周伟琳,俞云松,马亦林.超广谱β内酰胺酶的分类[J].中国抗感染化疗杂志,2002,2(4):245-248. 被引量：3
  • 3Naas T, Nordmann P. OXA type beta-lactamases [J]. Curr Pharm Des,1999,5(11) :865 - 879.
  • 4Poirel L,Gerome P, De Champs C , et al. Integron located oxa- 32 gene cassette encoding an extended spectrum variant of OXA-2 lactamase from Pseudomonas aeruginosa [J]. Antimicrob Agents Chemother, 2002,46(2) : 566 - 569.
  • 5Poirel L,Heritier C,Tolun V,etal. Emergence of oxacillinase- mediated resistance to imipenem in Klebsilla pneumoniae [J]. Antimierob Agents Chemother, 2004,48( 1 ) : 15 -22.
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  • 7Danel F, Hall L M, Livermore D M. Laboratory mutants of OXA-10 β-laetamase giving ceftazidime resistance in Pseudomonas aeruginosa [J]. J Antimicrob Chemother, 1999,43(3) : 339 - 344.
  • 8Weldhagen G,Poirel L, Nordmann P. Ambler class A extend ed spectrum beta lactamases in Pseudomonas aeruginosa : novel developments and clinical impact [J]. Antimicrob Agents Chemother,2003,47(8) :2385 - 2392.
  • 9Boo T W, Walsh F, Crowley B. First report of OXA~23 carbapenemase in clinical isolates of Acinetobacter species in the Irish Republic [J]. J Antimicrob Chemother, 2006,58(5):1101 - 1102.
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二级参考文献49

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共引文献15

同被引文献33

  • 1王春新,糜祖煌,常东.从绿脓假单胞菌中检出GES-5型超广谱β内酰胺酶[J].中华检验医学杂志,2006,29(9):845-846. 被引量：6
  • 2Kim S, Kim J, Kang Y, et al. Occurrence of extended ： spectrum 13 - lactamases in members of the genus Shigella in the Republic of Ko- rea[ J] Clin Mierobiol, 2004, 42( 11 ) : 5264 - 5269.
  • 3Andros P, Petroni A, Faccone D, et al. Extended - spectrum beta - lactamases in Shigella flexneri from Argentina: first report of TOHO - 1 outside Japan. Int[J] . Antimicrob Agents, 2005, 25(6) : 501 - 507.
  • 4Vasilev V, Japheth R, Yishai R, et al. Extended - spectrum beta - lactamase- producing Shigella strains in Israel, 2000 -2004. Eur [J] . Clin Microbiol Infect Dis, 2007, 26(3) : 189 -194.
  • 5Acikgoz ZC, Eser OK, Koreaz S, et al. CTX - M - 3 type beta - lactamase producing Shigella sonnei isolates from pediatric bacillary dysentery cases. Jpn[ J] Infect Dis, 2008. 61(2) : 135 - 137.
  • 6Cheung TK, Chu YW, Tsang GK, et al. Emergence of CTX - Mtype beta- lactam resistance in Shigella spp. in Hong Kong. Int[ J]. Antimicrob Agents, 2005, 25 (4) : 350 - 352.
  • 7Bauernfeind A, Grimm H, Schweighart S, et al. A new plasmidic cefotaximase in a clinical isolate of Escherichia coil[J]. Infection, 1990, 18(5) : 294 -298.
  • 8张卓然,夏梦岩,倪语星主编.微生物耐药的基础与临床.第1版.北京:人民卫生出版社,2007.127-130.
  • 9Bert F, Branger C, Lambert-Zechovsky N. Identification of PSE and OXA -lactamase genes in Pseudamanas aeruginosa using PCR-restriction frag ment length polymorphism. J Antimicrob Chemother,2002,50 : 11-18.
  • 10weldhagen G, Poirel L, Nordmann P. Ambler class A exterlded-spectrum beta-laetamases in Pseudomonas aeruginosa:novel developments and clin- ical impact. Antimicrob Agents Chemother,2003 ,47 :2385-2392.

引证文献6

二级引证文献10

中国感染控制杂志
2010年 第6期

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