期刊文献+

肾移植术后肺部感染的病原体分析与诊治 被引量:15

Pathogen Diagnosis and Management of Pulmonary Infection after Renal Transplantation
原文传递
导出
摘要 目的探讨肾移植术后肺部感染的病原体诊断,提高患者生存率。方法回顾性地分析2003年8月-2008年8月43例肾移植术后肺部感染患者临床资料。结果肾移植术后肺部感染的病原体主要有真菌(44.2%)、病毒(30.2%)、结核分枝杆菌(9.3%)和其他细菌(9.3%);出现时间一般在术后<6个月;曲霉菌属及卡氏肺囊虫性肺炎病死率高,分别为28.6%和16.7%。结论早期诊断及经验性治疗尤为重要,发病早期无特殊急重情况不建议联合治疗。 OBJECTIVE The discuss the pathogen diagnosis and management of pulmonary infection after renal transplantation to improve the patients survival rate after renal transplantation.METHODS A retrospective analysis was made on 43 cases of pulmonary infection after renal transplantation.RESULTS The main etiological microorganisms of pulmonary infection were fungi(44.2%),virus(30.2%),Mycobacterium tuberculosis(9.3%) and other bacteria(9.3%),mainly emerged within 6 months 2 cases were with polyinfection.Aspergillus and Pneumocystis carinii pneumonia led to high mortality rate,28.6% and 16.7% respectively.CONCLUSIONS Early diagnosis and empirical therapy are very important.The diagnosis and active treatment contribute to decrease the fatal cases.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2010年第23期3669-3671,共3页 Chinese Journal of Nosocomiology
基金 辽宁省教育厅高等学校科研项目(20060903)
关键词 肾移植 肺部感染 病原体 诊断 治疗 Kidney transplantation Pulmonary infection Pathogen Diagnosis Treatment
  • 相关文献

参考文献6

  • 1Varga M, Remport A,Czebe K,et al. Cytomegalovirus infec tion after solid-organ transplantation, its risk factors, direct and indirect effects and prevention strategies[J]. Orv Hetil, 2008,149(12) :551-558.
  • 2张勇,熊盛道.肾移植术后肺部感染的诊治进展[J].中华医院感染学杂志,2006,16(4):475-477. 被引量:11
  • 3侯瑞鹏,石炳毅,易滨,柏宏伟,赵豫波.肾移植术后院内与院外肺部感染的分析[J].中华医院感染学杂志,2008,18(1):53-55. 被引量:12
  • 4Park YS, Seo JB, Lee YK, et al. Radiological and clinical findings of pulmonary aspergillosis following solid organ transplant[J]. Clin Radiol,2008,63(6):673-680.
  • 5Einollahi B, Lessan-Pezeshki M, Pourfarziani V, et al. Invasive fungal infections following renal transplantation: a review of 2410 recipients[J]. Ann Transplant, 2008,13 (4): 55- 58.
  • 6Chen SY, Wang CX, Chen LZ, et al. Tuberculosis in Southern Chinese renal-transplant recipients [J]. Clin Transplant, 2008,22(6):780-784.

二级参考文献20

  • 1[1]Candan S,Pirat A,Varol G,et al.Respiratory problems in renal transplant recipients admitted to intensive care during long-term follow-up[J].Transplant Proc,2006,38(5):1354-1356.
  • 2[2]Linhares MM,Gonzalez AM,Trivno TV,et al.Simultaneous pancreas-kidney transplantation:infectious complications and microbiological aspects[J].Transplant Proc,2004,36(4):980-981.
  • 3[3]Kalra V,Agarwal SK,Khilnani GC,et al.Spectrum of pulmonary infections in renal transplant recipients in the tropics:a single center study[J].Int Urol Nephrol,2005,37(3):551-559.
  • 4Sarmieto TM, Dockrell DH, Schwab TR, et al. Mycophenolate mofetil increases cytomegalovirus invasive organ disease in renal transplant patients[J]. Clin Transplant, 2000, 14:136-138.
  • 5Anglicheau D, Lautrette A, Scieux C, et al. Lowering immunosuppression is safe and effective to treat altered pattern of CMV infection in renal transplant recipients on valciclovir prophylaxis[J]. Transplant Proc, 2002,34 (7): 2826-2827.
  • 6Shorr AF, Susla GM, Pharm D, et al. Pulmonary infiltrates in the non-HIV-infected immunocompromised patient: etiologies, diagnostic strategies, and outcomes[J]. Chest, 2004,125:260-271.
  • 7Linhares MM, Gonzalez AM, Trivino TV, et al. Simultaneous pancreas-kidney transplantation: infectious complications and microbiological aspects[J]. Transplant Proc,2004,36: 980-981.
  • 8Tveit DJ, Hypolite IO, Poropatich RK, et al. Hospitalizations for bacterial pneumonia after renal transplantation in the United States[J]. J Nephrol, 2002,15(3):255-262.
  • 9Durlik M. Comparison of antigenemia (pp65) assay and polymerase chain reaction in diagnosis of cytomegalovirus infection in renal transplant recipients treated with ATG[J]. Transplant Proc, 2000, 32(6): 1350-1352.
  • 10Marr KA, Carter RA, Crippa F, et al. Epidemiology and outcome of mould infection in hematopoietic stem cell transplant recipients[J]. Clin Infect Dis, 2002,34: 909-917.

共引文献20

同被引文献144

引证文献15

二级引证文献72

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部