摘要
目的 探讨冠状动脉狭窄的严重程度与冠脉危险因素的相关性及与心血管疾病的相关性.方法 对2008年10月至2010年7月在本院临床诊断或疑诊为冠心病并行冠脉造影的598例住院患者的临床资料进行分析,包括年龄、性别、血压、血糖、血脂、血尿酸、肾功能、老年性瓣膜病变、抑郁症、脑梗塞、心律失常类型等.对冠状动脉的狭窄程度进行分类.结果 采用单因素和多因素方法 分析结果 ：①单因素分析示：在冠脉狭窄逐渐增高的四组中,单个危险因素和危险因素数目的 百分比之间有明显统计学意义（P＜0.05）.②按冠脉病变有无分组,抑郁症、高尿酸血症、心肌桥的发病率有明显统计学意义,而心律失常、轻度肾功能不全、老年性瓣膜性病变的发病率无明显统计学意义.③多因素Logistic回归分析示,冠脉狭窄的危险因素为男性、老龄、高脂血症、糖尿病、高血压、抑郁症.结论 对冠心病的传统危险因素及新的危险因素如抑郁症、高尿酸血症的控制可进一步预防冠心病的发生.
Objective To evaluate the relationship between the severity of the coronary artery stenosis （CAS） and the cardiovascular risk factors. Methods The clinical datum of 598 in-department patients who diagnosed or suspected to have coronary heart disease （CHD） from the September of 2008 to 2010 received coronary angiography were analysed and studied. The relationship between the cardiovascular risk factors such as age, gender, blood pressure, blood glucose was analysed. Analyses were achieved by univariate and multivariate mellitus. Results （1）X^2 test analysis showed that in the four groups, the percentage of the single risk factor and amounts of the risk factors were enhanced gradually. （2）The patients were divided into two groups according to coronary lesions, the incidence of depression, hyperuricemia and myocardial bridge were significantly difference, but the incidence of arrhythmia, mild renal insufficiency and senile valvular disease were no statistical significance. （3）Multiple regression analyses indicated that risk old, male, hyperlipidemia, diabetes, hypertension and depression were the risk factors for coronary artery stenosis. Conclusion Depression and hyperuricemia may be the new risk factors for coronary artery disease.
出处
《中国心血管病研究》
CAS
2010年第12期898-900,共3页
Chinese Journal of Cardiovascular Research
关键词
冠状动脉造影术
冠脉狭窄
危险因素
Coronary angiography
Coronary artery stenosis
Risk factors
