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肾鹿角形结石患者结石成分的红外光谱分析 被引量:12

Infrared spectrophotometry for crystalline composition of staghorn calculi
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摘要 目的 通过红外光谱分析法分析肾鹿角形结石的化学成分,探讨其与泌尿系统感染的关系,为肾结石的治疗和预防提供帮助.方法 回顾性分析北京大学人民医院泌尿外科2009年8月至2010年2月共51例肾鹿角形结石病例,以红外光谱法分析结石的化学成分,并对尿/结石细菌培养等临床资料进行总结.结果 共检测出一水草酸钙、二水草酸钙、碳酸磷灰石、六水磷酸镁铵、尿酸、L-胱氨酸等6种化学成分.结石以混合成分为主,单一成分结石15例(29.4%).含钙结石41例(80.4%),含尿酸结石10例(19.6%).感染石26例(51.0%).术前尿常规阳性率78.4%(40/51),尿/结石细菌学培养阳性率64.7%(33/51).结论 肾鹿角形结石成分多样,病因复杂,与泌尿系统感染密切相关. Objective To provide theoretic rationales for treatment and prevention of staghoru calculi by analyzing stone composition and studying the relationship between stone and urinary tract infections. Methods The clinical data of 51 staghorn calculi patients were analyzed retrospectively. The stone compositions were studied by infrared spectrophotometry. Results Six types of stone compositions were obtained. There were calcium oxalate monohydrate, calcium oxalate dehydrate, carbonate apatite, magnesium ammonium phosphate hexahydrate, uric acid and L-eystine. The majority of stones were of mixed compositions,pure stones were found in 15 cases (29.4%). Among all stones, calcium oxalate stones were found in 41 cases ( 80. 4% ) and uric stones in 10 cases ( 19. 6% ). Infectious stones were found in 26 cases (51.0%). Urinary tract infections were found in 40 (78.4%) patients and positive urine/stone culture was detected in 33 (64. 7% ) patients. Conclusion With multiple crystalline compositions and etiological factors, the staghoru calculi are closely correlated with urinary tract infections.
出处 《中华医学杂志》 CAS CSCD 北大核心 2010年第44期3150-3152,共3页 National Medical Journal of China
关键词 肾结石 光谱分析 鹿角形结石 Kidney calculi Spectrum analysis Staghoru calculi
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