摘要
目的解读三维相干光学断层扫描（3D—OCT）图像上视网膜外界膜（OLM）、视细胞的内外节连接带（IS／OS）和视网膜色素上皮（RPE）层的三条高反射带的组成及其临床意义。方法应用视网膜胚胎学、组织学的知识，结合3个病例的3D—OCT图像特征．解读视网膜外层及RPE层的反射带组构。结果视网膜RPE层内侧极高反射带是由RPE细胞顶端的绒毛突、黑色素颗粒和可能还有闭锁小带，以及嵌入RPE细胞顶端绒毛突中视细胞外节末端的盘膜共同形成；外侧的极高反射带是由RPE基底细胞膜的大量内伸的皱褶和玻璃膜共同形成；而RPE层中间的细窄的较高反射带可能主要是由RPE细胞核组成。结论视网膜的显微结构知识及临床病例的图像研读对认知三维相干光学断层扫描图像的视网膜外层反射带的组成，具有重要的意义。
Objective To interpret the nature of the reflections in outer limiting membrane （OLM）, IS/OS and the retinal pigment epithelium （RPE） layer on the three-dimensional optical coherence tomography （3D-OCT）. Methods Knowledge of ocular embryology and histology combined with 3D-OCT image feature of clinically relevant cases to interpret the outer retina and RPE layer. Results The highly inner reflective band of RPE layer is composed of the microvilli processes at apex of RPE, melanin granules and possibly tight junctions （zonula occludens）, as well as the apical portions of outer segment which is embedded in the villous processes of RPE cells. The highly outer reflective band of RPE layer comprises the numerous highly convoluted basal enfolding of the cell membrane at the basilar surface of RPE cells and Bruch＇s membrane （BM）. While the middle of RPE layer with a higher reflectance may be mainly composed of RPE cell nuclei. Conclusion Ultra structure of retina and information of pathology ＆ physiology for interpretation of the images of OCT has the vital significance.
出处
《中华眼视光学与视觉科学杂志》
CAS
2010年第5期324-328,共5页
Chinese Journal Of Optometry Ophthalmology And Visual Science
