摘要
目的分析南京地区人群的峰值骨量及骨密度变化的规律。方法 10599例受试者被分为两组,A组为9795例的男性和女性,B组为804例有脆性骨折的女性,所有入选人群均行双能X线骨密度测量仪测量腰椎和髋部的骨密度(BMD)。将A组按5岁为一年龄组,分为14组,B组按10岁为一年龄组,分为4组。结果男性腰椎骨峰值年龄出现在30～34岁,股骨颈,Ward's三角及大转子的骨峰值年龄在25～29岁;女性腰椎骨峰值出现在35～39岁,股骨颈,Ward's三角及大转子骨峰值年龄在30～34岁。脆性骨折女性各部位的BMD均丢失明显。结论 南京地区男性35岁后和女性40岁后骨量将逐渐下降,脆性骨折患者骨密度丢失显著。50岁以上女性和65岁以上男性应重视骨密度的定期检查。
Objective The aims of this study were to analyze the peak bone mass and the role of changes of bone mineral density （BMD） in Nanjing residents. Methods Ten thousand and six hundred people were included and divided into 2 groups. Group A included 9795 males and females. Group B included 804 females with fragility fracture. BMDs of the lumbar spine and the left hip were measured with dual energy X- ray absorptiometry. Group A was divided into 14 subgroups by 5 years of age. Group B was divided into 4 subgroups by 10 years of age. Results In men, peak BMD values were observed in the lumbar spine at 30- 34 years old, in the femoral neck, trochanter, and Ward＇s triangle at 25-29 years old. In women, peak BMDs appeared in the lumbar spine at 35-39 years old, in the femoral neck, trochanter, and Ward＇s triangle at 30-34 years old. Significant loss of BMD was found in all measured sites in fragility fracture women at age 40 and beyond. Conclusion BMD was gradually decreased in men at 35 years and older and in women at 40 years and older in Nanjing. The BMD in fragility fracture patients was significantly lost. Women aged 50 years and older and men aged 65 years and older should pay more attention on regular BMD examination.
出处
《中国骨质疏松杂志》
CAS
CSCD
2010年第11期836-839,共4页
Chinese Journal of Osteoporosis
基金
南京市卫生局发展基金项目(编号YKK08130)
关键词
骨密度骨
质疏松
骨折
Bone mineral density
Osteoporosis
Fracture
