期刊文献+

颈外静脉留置针配合化疗泵在FOLFOX方案中的应用

下载PDF
导出
摘要 目的:探讨FOLFOX方案中采用颈外静脉留置针配合化疗泵治疗胃肠道恶性肿瘤的效果。方法:选择采用经颈外静脉留置针应用奥沙利铂及5-FU化疗泵的病人35例为A组,应用上肢浅静脉留置针分次滴注奥沙利铂及5-FU化疗的病人35例为B组,观察两组病人用药后末梢神经炎和静脉炎的发生率以及化疗疗效的改善情况。结果:A组和B组末梢神经炎发生率分别为5.7%和74.2%,静脉炎的发生率分别为8.5%和48.5%,A、B两组完全缓解率分别为17.1%、6.7%。两组数据经Wilcoxon秩和检验,差异具有统计学意义(P<0.05)。结论:颈外静脉留置针配合化疗泵的使用可明显降低化疗副反应,提高化疗疗效,改善病人生活质量,值得临床推广。
出处 《护理实践与研究》 2011年第1期98-99,共2页 Nursing Practice and Research
  • 相关文献

参考文献4

二级参考文献25

  • 1钱军,秦叔逵,梅静峰,陈映霞,邵志坚,何泽明.奥沙利铂联合卡培他滨二线治疗晚期胃癌的临床观察[J].中华肿瘤杂志,2004,26(12):746-748. 被引量:60
  • 2石玉中,寇振芬,张利国,马长花.癌症患者的述情障碍[J].中国临床心理学杂志,1996,4(3):175-176. 被引量:23
  • 3罗飞燕,李健鸿,梁洁珍.癌症患者PICC置管化疗的护理[J].现代护理,2006,12(13):1250-1251. 被引量:59
  • 4陈利君,徐光炜.肿瘤学.天津:天津科学技术出版社,1996:669-670.
  • 5Moiseyenko VM,Ajani JA,Tjulandin SA,et al.Final results of a randomized controlled phase Ⅲ trial (TAX 325) comparing docetaxel (T) combined with cisplatin (C) and 5-fluorouracil (F)to CF in patients (pts) with metastatic gastric adenocarcinoma (MGC)[ J ].J Clin Onc,Proc Am Soc Clin Oncol,2005,23:Abstract 4002.
  • 6Al-Batran S,Hartmann J,Probst S,et al.A randomized phase Ⅲ trial in patients with advanced adenocarcinoma of the stomach receiving first-line chemotherapy with fluorouracil,leucovorin and oxaliplatin (FLO) versus fluorouracil,leucovorin and cisplatin (FLP)[J].J Clin Onc,Proc Am Soc Clin Oncol,2006,24:Abstract 4016.
  • 7Bugat R.Irinotecan in the treatment of gastric cancer[J].Ann Oncol,2003,14(Suppl 2):37 -40.
  • 8Bouche O,Raoul JL,Bonnetain F,et al.Randomized multicenter phase Ⅱ trial of a biweekly regimen of fluorouracil and leucovorin (LV5FU2),LV5FU2 plus cisplatin,or LV5FU2 plus irinotecan in patients with previously untreated metastatic gastric cancer:a Federation Francophone de Cancerologie Digestive Group Study-FFCD 9803[ J].J Clin Oncol,2004,22 (21):4319-4328.
  • 9Fazio N,Zampino G,Nol F,et al.Irinotecan combined with in fusional 5-fluorouracil and folinic acid (folfiri) in patients with metastatic gastric cancer resistant to cisplatin-containing chemo therapy[J].J Clin Onc,Proc Am Soc Clin Oncol,2004,22:Abstract 4146a.
  • 10Peeters M,Van Laethem JL,Baert F,et al.Phase Ⅱ study of irinotecan+ 5FU/FA for patients with previously treated ad vanced gastric cancer[J].J Clin Onc,Proc Am Soc Clin Oncol,2004,22:Abstract 4076a.

共引文献272

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部