摘要
目的:观察耳穴穴位注射野木瓜注射液(IS)治疗中重度癌痛的临床疗效。方法:将152例患者随机分为2组,治疗组予IS耳穴穴位注射联合奥施康定口服治疗,对照组予奥施康定口服治疗,观察2组镇痛缓解率、起效时间、镇痛维持时间,填写简明疼痛调查表(BPQ)。结果:2组中度及以上缓解率、总体缓解率分别比较,差异均无显著性意义(P>0.05);2组各程度疼痛镇痛药用量比较,差异均有显著性意义(P<0.05);2组平均镇痛起效时间和平均镇痛维持时间分别比较,差异均有非常显著性意义(P<0.01)。2组治疗后在日常生活、情绪、行走能力、睡眠、生活乐趣及总积分分别与治疗前比较,差异均有非常显著性意义(P<0.01)。治疗组治疗后在日常生活、情绪、睡眠、生活乐趣及总积分分别与对照组比较,差异均有显著性意义(P<0.05)。结论:耳穴穴位注射IS治疗癌痛有较好的临床疗效,安全性高,配合奥施康定治疗,镇痛起效时间更快,镇痛维持时间更长;减少了奥施康定剂量,不良反应更少,进一步改善了患者生活质量。
Objective： To observe the analgesic effect of ear acupoint injection of Injection Stauntoniae （IS） on the moderate and severe cancer pain. Methods： One hundred and fifty-two patients with moderate and severe cancer pain were divided into two groups randomly. Seventy-seven patients in the treatment group were treated with ear acupoint injection of IS combined with oral use of oxycontin tablets, and seventy-five patients in the control group received oxycontin tablets alone. Effective rate for analgesia, time for onset of analgesic effect, duration of analgesic effect, and BPQ score were observed. Results： No statistical significant difference was found in the total effective rate and obvious remission rate between two groups （P 〉 0.05）. The total dosage of oxycontin in the treatment group was significantly lower than that in the control group （P 〈 0.05）. The mean time for onset of analgesic and mean duration of analgesic effect in the treatment group were significantly different from those in the control group （P 〈 0.01）. The scores of activities of daily life （ADL）, emotion, walking ability, sleeping, and life joy as well as the total score of quality of life （QOL） were improved significantly in both groups after treatment （P 〈 0.01 compared with those before treatment）, and the improvement of the scores of ADL, emotion, sleeping, and life joy as well as total score of QOL was obvious in the treatment group （P 〈 0.05 compared with that in the control group）. Conclusion： Ear acupoint injection of IS is effective and safe to relieve cancer pain, and exerts a rapid and long-term analgesic effect when used together with oxycontin. Ear acupoint injection of IS can decrease the dosage of oxycontin, and improve the QOL of patients with less side effect.
出处
《新中医》
CAS
北大核心
2011年第1期113-115,共3页
New Chinese Medicine
基金
广东省中医药管理局科研课题(编号:2008261)
关键词
癌痛
耳穴
穴位注射
野木瓜注射液
奥施康定
Cancer Pain
EarAcupoint
Acupoint Injection
Injection Stauntoniae
Oxycontin
