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5%咪喹莫特乳膏联合电灼治疗尖锐湿疣的疗效观察 被引量:24

Observation on Therapeutic Efficacy of Condyloma Acuminatum with 5%Imiquimod Cream Combined with Electrocautery
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摘要 目的观察咪喹莫特乳膏联合电灼治疗尖锐湿疣(CA)的临床疗效。方法将入选的98例CA患者随机分为三组,A组采用单纯电灼治疗,B组采用卡介菌多糖核酸针联合电灼治疗,C组采用5%咪喹莫特乳膏联合电灼治疗,6个月后分别对比三组患者的治愈率及复发率。结果通过6个月的治疗和随访,A,B,C组治愈率分别是58.06%,81.82%,90.90%;复发率分别是41.94%,18.18%,9.10%,其中A组与B,C两组差异有统计学意义(P均<0.05)。结论 5%咪喹莫特乳膏联合电灼治疗CA治愈率高、复发率低。 Objective To investigate the clinical effect of 5% imiquimod cream with the electrocautery in the treatment on condyloma acuminatum(CA). Methods Ninety-eight patients of CA were randomized into three groups. The patients in group A, B and C were respectively treated with the single electrocautery, the electrocautery combined with injection with polysaccharide nucleic acid fraction of bacillus calmette Guerin (BCG-PSN) , and the electrocautery with 5% irniquimod cream. The recovery rates and the recurrent rates of the CA patients were analyzed statistically after six monthes. Results The recovery rates in group A , B and C were 58.06% ,81.82% ,90.90% and the recurrent rates were 41.94% , 18. 18% and 9. 10% respectively. There were significant differences either between groups A and B or groups A and C (P 〈0.05) . Conclusion 5% imiquimod cream with the electrocautery in treatment of CA has the higher recovery rate and the lower recurrent rate.
作者 徐萍 赵小兴
出处 《中国皮肤性病学杂志》 CAS 北大核心 2011年第1期80-81,共2页 The Chinese Journal of Dermatovenereology
关键词 5%咪喹莫特乳膏 卡介菌多糖核酸 电灼 尖锐湿疣 5 % Imiquimod cream BCG-PSN Electrocautery Condyloma acuminatum (CA)
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