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胎儿动脉导管收缩或早闭的早期诊断与治疗并文献分析 被引量:6

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摘要 目的探讨胎儿动脉导管收缩或早闭的早期临床诊断及处理。方法报道胎儿动脉导管收缩导致右心功能衰竭1例,并收集近年文献进行复习,总结该疾病的临床表现、诊断、处理及患儿预后。结果收集近年来12篇胎儿动脉导管收缩或早闭的文献,共33例,其中5例母亲孕期有使用前列腺素合成酶抑制剂病史,胎儿心脏彩色超声均提示动脉导管不同程度的收缩或关闭,部分伴有右心室、右心房扩大,右心室肥大,三尖瓣或肺动脉瓣反流,肺动脉扩张及胎儿水肿。5例死亡,其余病例均存活,绝大部分病例预后良好,2例头颅MRI提示缺氧缺血性脑病(HIE)。结论母亲无使用前列腺素合成酶抑制剂史的胎儿亦可以发生动脉导管收缩或早闭,产前超声对该疾病的诊断具有重要意义,早期诊断并适时终止妊娠可以挽救患儿生命,大部分患儿预后良好。
出处 《中华临床医师杂志(电子版)》 CAS 2010年第11期I0015-I0018,共4页 Chinese Journal of Clinicians(Electronic Edition)
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共引文献31

同被引文献30

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