摘要
目的了解重症监护病房铜绿假单胞菌的耐药情况,为临床合理用药提供实验室依据。方法对本院2008年7月～2009年10月各重症监护病房各类送检标本常规进行病原菌培养、鉴定和药敏试验,统计分析铜绿假单胞菌的临床分离株的标本分布及耐药情况。结果从临床送检的各类标本中分离出铜绿假单胞菌101株,其中痰标本65株,占64.3%,该菌对氨苄西林的耐药率最高(98%),对多粘菌素E的耐药率最低(8.9%),其次对美罗培南的耐药率较低(33.7%),对于其它的抗菌药物均呈现不同程度的耐药。结论重症监护病房铜绿假单胞菌的感染率很高,其耐药性严重,临床应根据药敏结果合理用药。
Objective To investigate the clinical distribution and drug resistance of P.aeruginosa infection in the ICU of our hospital and provide basis for rational drug therapy.Methods Samples isolated from ICU between July 2008 and October 2009 were carried out routine culture and identification for pathogenic bacteria.And drug sensitivity test was performed.Clinical distribution and drug resistance of P.aeruginosa were obtained by statistical analysis.Results 101 P.aeruginosa strains were derived from clinical specimens,and most isolated from sputum samples accounting for 65（64. 3%）.Drug resistant rate of P.aeruginosa to ampicillin was the highest（98%）,to meropenem was lower（33.7%）,to polymyxin E was the lowest（8.9%）.And resistance to other antimicrobial agents varied.Conclusions The rate of P. aeruginosa infection in ICU is highly prominent,and its drug resistance and multiple drug resistance are serious.Antimicrobial treatment to P.aeruginosa infection should be guided by drug sensitivity test.
出处
《南华大学学报（医学版）》
2010年第6期779-781,共3页
Journal of Nanhua University(Medical Edition)
