摘要
目的研究Mg2+在喹诺酮类药物无菌检查法中的应用。方法在培养基中加入不同浓度的Mg2+,观察不同方法中6种阳性对照菌的生长情况。结果 Mg2+浓度对消除喹诺酮类药物的抑菌性有不同的影响。结论 Mg2+浓度为0.2 mol/L的培养基能有效消除喹诺酮类药物的抑菌性。
Objective To study the application of Mg2＋in the sterility test of quinolones.Methods The growth of 6 positive control bacteria was observed after adding different concentrations of Mg2＋into culture medium.Results According to the results,the antimicrobial activity of quinolones was affected by the concentration of Mg2＋in some extent.Conclusion The culture medium with 0.2 mol/L Mg2＋could effectively eliminate the antimicrobial effect of quinolones.
出处
《中国药业》
CAS
2011年第1期28-29,共2页
China Pharmaceuticals
