摘要
目的:建立紫外分光光度法测定阿普唑仑片含量的不确定度的评定方法。方法:从吸收度、体积、称量等来源中找出本实验室采用紫外分光光度法测定阿普唑仑片含量时影响不确定度的主要因素,分别对各不确定度因素进行分析、评估及合成。结果:影响不确定度的主要因素来源于仪器;取k=2(置信概率95%)计算出的紫外分光光度法测定阿普唑仑片含量的标准不确定度及扩展不确定度分别为0.59%和1.18%。结论:本实验室紫外分光光度法测定阿普唑仑片含量的结果是可靠且可控的。
OBJECTIVE：To establish a method for uncertainty evaluation of the content determination of Alprazolam tablets by UV spectrophotometry.METHODS：The main factors of the uncertainty of UV spectrophotometry for content determination of Alprazolam tablets in our laboratory were found out in terms of absorbency,volume and quantity,etc.The uncertainty of determination method was analyzed,evaluated and synthesized.RESULTS：The main factor of uncertainty was apparatus;by using a covage factor k=2（confidence level of 95%）,standard and extend uncertainty were assessed as 0.59% and 1.18% respectively.CONCLUSION：UV spectrophotometry is reliable and controllable for the content determination of Alprazolam tablets in our laboratory.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第1期50-51,共2页
China Pharmacy
关键词
阿普唑仑片
紫外分光光度法
含量测定
不确定度
评定
Alprazolam tablets
UV spectrophotometry
Content determination
Uncertainty
Evaluation
