摘要
目的探讨老年人消化性溃疡临床特点,为其预防和治疗提供依据。方法收集2006年5月至2010年5月入住我院60岁及以上的全部消化性溃疡患者84例为研究组,选择同期住院的60岁以上的慢性胃炎患者123例作为对照组1,遵循同性别、同民族、同发病月份及同胃镜结果的条件,选择同期住院的60岁以下的消化性溃疡患者138例作为对照组2。对其相关因素进行多因素Logistic回归分析。结果 Logistic回归分析显示Hp感染、服用非甾体类消炎药(NSAID s)、吸烟、饮酒及患抑郁症对老年人消化性溃疡的预后有意义,其中幽门螺杆菌(Hp)感染、服用NSAID s与老年人消化性溃疡密切相关,吸烟、饮酒、患抑郁症是老年人消化性溃疡的危险因素,服用NSAID s是老年消化性溃疡并出血的独立危险因素。结论临床在评价上述相关危险因素后可早期评估老年人消化性溃疡预后,早期制定相应的防治措施。
Objective To investigate the clinical features of peptic ulcer （ PU） in the aged in order to provide a reliable basis for the prevention and treatment of PU. Methods We took 84 PU patients of and above 60 years old in our Hospital from May 2006 to May 2010 as the treatment groups ,while 123 chronic gastritis patients above 60 years old as control groups 1 and 138 PU patients under 60 years old as control groups 2. All the patients were in the same of condition in sex, nationality, onset month and endoscopic findings. The risk factors of PU in the aged were analyzed by multivariate logistic regression analysis. Results Logistic regression analysis showed that Hp infection, NSAIDs intake, cigarette use, alcohol intake and depression were determined as prognostic factors for the aged patients with PU. Conclusion The risk factors closely related to the occurrence of PU in the aged are Hp infection, NSAIDs intake, cigarette use, alcohol intake and depression,in which NSAIDs intake is an independent risk factor for bleeding in the aged with PU.
出处
《实用医院临床杂志》
2011年第1期65-67,共3页
Practical Journal of Clinical Medicine
