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光镊在生物细胞及生物大分子中的应用研究 被引量:2

Application of optical tweezers in biological cell and biopolymer
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摘要 利用光镊技术研究生物微粒是目前生物领域的一个研究热点,介绍了光镊基本装置及在生物大分子中力的一般标定法,同时系统地归纳了光镊技术在生物细胞和生物大分子上的理论和实验研究成果。主要有细胞的操控、细胞的应变能力和细胞膜弹性方面的实验研究成果;对于生物大分子中的DNA,RNA等方面的实验研究;最后介绍了光镊结合其他技术在生物领域中的应用。 The study of biological particle in optical tweezers has become a research hotspot in biology territory.In this paper,the basic device of optical tweezers and the standardization of force in biopolymers are simply introduced.Meanwhile,the experimental and theoretical results of optical tweezers in biological cell and biopolymers are reviewed.There are many results in experiment,we mainly introduce the manipulation of cells,the stress response of cells and the elasticity of cellularity,respectively.For biological molecules,the aspects of DNA/RNA and so on are given in this paper.In the end,the application of the combination of optical tweezers and other technologies in biology are present.
机构地区 燕山大学理学院
出处 《激光与红外》 CAS CSCD 北大核心 2011年第1期31-36,共6页 Laser & Infrared
基金 国家自然科学基金项目(No.50875232)资助
关键词 光镊技术 微操纵 生物细胞 生物大分子 optical tweezers technology biological cells biopolymers micro-manipulation
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  • 1A Ashkin, J M Dzie dic, J E Bjorkholm, et al. Observation of a single-beam gradient force optical trap for dielectric particles[ J ]. Opt. Lett. , 1986,11 (5) :288 - 290.
  • 2D Matthews. Biophotonics focused on grand challenges in medicine and bioscience [ C ]. Presentation to Britton Chance Center for Biomedical Optics-Wuhan, China, October, 28,2008.
  • 3姚建铨,安源,赵海泉.光镊技术的发展与应用[J].光电子.激光,2004,15(1):123-128. 被引量:14
  • 4John S D W L, Robert S, Waslter G. Elasticity of the red cell membrane and its relation to hemolytic disorders:An optical tweezers study [ J ]. Biophys J, 1999, 77: 3085 - 3095.
  • 5喻有理,张镇西,李政.球模型生物细胞在光镊势阱中的动力学分析[J].光子学报,2005,34(10):1582-1585. 被引量:5
  • 6A Ashkin. J M Dziedzic. Optical trapping and manipulation of viruses and bacteric [ J ]. Science, 1987, 235 : 1517 - 1520.
  • 7吕巍,朱艳英,沈军峰,窦红星.毛细管中生物细胞的光微操纵实验研究[J].激光与红外,2010,40(5):467-470. 被引量:1
  • 8Y Hayashi, S Ashihara, T Shimura, et al. Particle sorting using optically induced asymmetric double well potentia [ J ]. Opt. Common. ,2008,281 (14) :3792 - 3798.
  • 9严秋劳,张镇西,喻有理,隆弢.细胞表面电荷的光镊测量方法及应用研究[J].激光生物学报,2008,17(2):261-264. 被引量:3
  • 10Guenther Leitz, Erik Fallman, Simon Tuck, et al. Stree respense in caenorhabditis elegans caused by optical tweez- ers : wavelength, power and time dependence [ J ]. Biophys J,2002,82 (4) :2224 - 2231.

二级参考文献140

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同被引文献32

  • 1刘春香,郭红莲,降雨强,李兆霖,程丙英,张道中.光镊系统中光放大倍数对测量结果的影响[J].物理学报,2005,54(3):1162-1166. 被引量:7
  • 2XIE Y,YANG H J,LIU K,et al.Visual servoing methods in robot-assist cell microinjection system[C]//Proceedings of the 13thIEEE Conference on Nanotechnology(IEEE-NANO).Beijing,China,2013:195-198.
  • 3HUANG H,SUN D,SU H,et al.Force sensing and control in robot-assisted suspended cell injection system[M].GULREZ T,HASSANIEN A E.Advances in Robotics and Virtual Reality.Berlin:Springer Berlin Heidelberg,2012:61-88.
  • 4FRANK T,DOERING L,HEINRICH G,et al.Silicon cantilevers with piezo-resistive measuring bridge for tactile line measurement[J].Microsystem Technologies,2014,20(4):927-931.
  • 5PANDYA H J,KIM H T,DESAI J P.A microscale piezoresistive force sensor for nanoindentation of biological cells and tissues[C]//Proceedings of ASME2013 Dynamic Systems and Control Conference.Palo Alto,California,USA,2013:V002T29A003-1-V002T29A003-5.
  • 6KOMATI B,AGNUS J,CLVY C,et al.Prototyping of a highly performant and integrated piezoresistive force sensor for microscale applications[J].Journal of Micromechanics and Microengineering,2014,24(3):1-34.
  • 7CAPPELLERI D J,PIAZZA G,KUMAR V.A two dimensional vision-based force sensor for microrobotic applications[J].Sensors and Actuators:A,2011,171(2):340-351.
  • 8KIM K,SUN Y,VOYLES R M,et al.Calibration of multiaxis MEMS force sensors using the shape-from-motion method[J].IEEE Sensors Journal,2007,7(3):344-351.
  • 9KISHINO A,YANAGIDA T.Force measurements by micromanipulation of a single actin filament by glass needles[J].Nature,1988,334(6177):74-76.
  • 10ISHIJIMA A,KOJIMA H,HIGUCHI H,et al.Multiple-and single-molecule analysis of the actomyosin motor by nanometer-piconewton manipulation with a microneedle:unitary steps and forces[J].Biophysical Journal,1996,70(1):383-400.

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