期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

γ-干扰素诱导蛋白10与风湿性疾病关系的研究进展 被引量：2

Progress on the study of the relationship between IP - 10 and rheumatic diseases
原文传递
导出
摘要 γ-干扰素诱导蛋白10（IP-10）是CXC类趋化因子之一，CXCR3是其唯一受体。研究表明：IP-10具有重要的生物学功能，参与多种疾病的发生，与多种风湿性疾病关系密切，主要介导Th1型炎症反应，还可抑制新生血管形成。另外，测定IP-10水平也可对某些风湿性疾病进行活动度评价、预后判断以及治疗决策指导。 IP-10 is a member of the CXC chemokine family. CXCR3 is the unique receptor of IP-10. Studies have shown that IP-10 is involved in rheumatic diseases by mediating Th1-type inflammatory response and inhibiting angiogenesis. In addition, detecting the level of IP-10 can be helpful in the assessment of the activity of certain rheumatic diseases, and guide the evaluation of the disease progression and deseision-making for the treatment.
作者 邹宗毅 唐雪梅
机构地区 重庆医科大学附属儿童医院肾脏免疫科
出处 《国际免疫学杂志》 CAS 北大核心 2011年第1期65-68,80,共5页 International Journal of Immunology
关键词 γ-干扰素诱导蛋白10 系统性红斑狼疮 类风湿关节炎 幼年特发性关节炎 IP-10/CXCL10 Systemic lupus erythematosus Rheumatoid arthritis Juvenile idiopathic arthritis
分类号 R593 [医药卫生—内科学]
  • 相关文献

参考文献25

  • 1Luster AD, Unkeless JC, Ravetch JV. Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature, 1985,315 (6021) :672-676.
  • 2Gerard C, Rollins BJ. Chemokines and disease. Nat Immunol, 2001,2(2) :108-115.
  • 3Lee EY, Lee ZH, Song YW. CXCL10 and autoimmune diseases. Autoimmun ,2009,8 ( 5 ) : 379-383.
  • 4张春梅,李著华.干扰素诱导蛋白10的研究进展[J].黑龙江医学,2006,30(6):424-426. 被引量：4
  • 5Wiley R, Palmer K, Gajewska B, et al. Expression of the Thl chemokine IFN-γ inducible protein 10 in the airway alters mucosal allergic sensitization in mice. J Immunol,2001,166 (4) :2750-2759.
  • 6Lasagni L, Francalanci M, Annunziato F, et al. An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J Exp Med, 2003,197 ( 11 ) : 1537-1549.
  • 7Lazzeri E, Romagnani P. CXCR3-binding chemokines: novel multifunctional therapeutic targets. Curt Drug Targets Immune Endocr Metabol Disord,2005,5( 1 ) :109-118.
  • 8李文庭,贺永文.γ-干扰素诱导蛋白10与疾病关系的研究进展[J].国际流行病学传染病学杂志,2006,33(3):201-203. 被引量：2
  • 9Hayashi T. Therapeutic strategies for SLE involving cytokines: mechanism-oriented therapies especially IFN-gamma targeting gene therapy. J Biomed Biotechno1,2010,2010. Pii :461641. Epub 2010 Aug 17.
  • 10Wenzel J,Woirenkamper E, Freutel S, et al. Enhanced type I interferon signalling promotes Thl-biased inflammation in cutaneous lupus erythematosus. J Pathol, 2005,205 ( 4 ) :435 ~442.

二级参考文献21

  • 1Dong Li,Su-Wen Zhu,Dong-Juan Liu,Guo-Liang Liu.Expression of interferon inducible protein-10 in pancreas of mice[J].World Journal of Gastroenterology,2005,11(30):4750-4752. 被引量：4
  • 2Baggiolini M,Dewald B,Moser B.Human chemokines:an update.Annu Rev Immunol,1997,15:675-705.
  • 3Walrath J,Zukowski L,Krywiak A,et al.Resident Th1-like effector memory cells in pulmonary recall responses to Mycobacterium tuberculosis.Am J Respir Cell Mol Biol,2005,33(1):48-55.
  • 4Mitra DK,Sharma SK,Dinda AK,et al.Polarized helper T cells in tubercular pleural effusion:phenotypic identity and selective recruitment.Eur J Immnnol,2005,35(8):2367-2375.
  • 5Okamoto M,Kawabe T,Iwasaki Y,et al.Evaluation of interferon-gamma,interferon-gamma-inducing cytokines,and interferon-gamma-inducible chemokines in tuberculous pleural effusions.Lab Clin Med,2005,145(2):88-93.
  • 6Azzurri A,Sow OY,Amedei A,et al.IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring inflammation and disease activity in Mycobacterium tuberculosis infection.Microbes Infect,2005,7(1):1-8.
  • 7Law HK,Cheung CY,Ng HY,et al.Chemokine upregulation in SARS coronavirus infected human nonocyte derived dendritic cells.Blood,2005,106(7):2366-2374.
  • 8Ng PC,Lam CW,Li AM,et al.Chemokine response in children with SARS.Arch Dis Child,2005,90(4):422-423.
  • 9Ward SE,Louffy MR,Blatt LM,et al.Dynamic changes in clinical features and cytokine/chemokine responses in SARS patients treated with interferon alfacon-1 plus corticosteroids.Antivir Ther,2005,10(2):263-275.
  • 10Lasarte JJ,Sarobe P,Boya P,et al.A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage.Hepatology,2003,37(2):461-470.

共引文献4

同被引文献17

  • 1刘先宁,朱秀平,杨华,陶沙.纸片扩散法对泪液中溶菌酶的测定[J].眼科研究,2005,23(2):154-154. 被引量：3
  • 2Kong KO, Tan AW, Thong BY, et al. Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus [J]. Clin Exp Immunol, 2009,156( 1 ) : 134-140.
  • 3Kong KO, Tan AW, Thong BY, et al. Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus [J]. Clin Exp Immunol, 2009,156 ( 1 ) : 134-140.
  • 4Arai Y, Arihiro S, Matsuura T, et al. Pmstaglandin E-major urinary metabolite as a reliable surrogate marker for mucosal inflammation in ulcerative colitis [J]. Inflamm Bowel Dis, 2014, 20(7) : 1208-1216.
  • 5Schoepfer AM, Beglinger C, Straumann A, et al. Fecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis than the Lichtiger Index, C-reactive protein, platelets, hemoglobin, and blood leukocytes [J ]. Inflamm Bowel Dis, 2013,19(2) :332-341.
  • 6Noguchi A, Watanabe K, Narumi S, et al. The production of interferon-gamma-inducible protein 10 by granulocytes and monoeytes is associated with ulcerative colitis disease activity [ J ]. J Gastroenterol, 2007,42 (12) : 947 -956.
  • 7张玉明,王芳芳,李宝贞,何艳,彭燕一.干燥综合征患者干眼病的临床分析[J].中华风湿病学杂志,2012,16(8):523-526. 被引量：14
  • 8无,胡品津.炎症性肠病诊断与治疗的共识意见（2012年，广州）[J].中华消化杂志,2012,32(12):796-813. 被引量：528
  • 9尹志华,曹智君,戴莉萍,罗秀霞,叶志中,周敏,张春容.系统性红斑狼疮患者6种细胞因子的血清水平[J].风湿病与关节炎,2014,3(3):14-16. 被引量：7
  • 10刘佳庆,张立,孙海柏,吴敏,杜岩青,冯爽,刘树业.液态芯片技术联合检测IFN-γ和IP-10诊断结核性胸腔积液[J].天津医药,2014,42(9):943-945. 被引量：4

引证文献2

二级引证文献2

国际免疫学杂志
2011年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部