摘要
目的了解尿抗原测定方法用于快速诊断社区获得性肺炎链球菌及军团菌感染的临床意义及我院社区获得性肺炎病原学特点。方法收集2009年11月—2010年3月我院门诊及住院社区获得性肺炎的患者,用免疫色谱层析法测定肺炎链球菌及军团菌尿抗原,对痰进行细菌分离培养与鉴定。住院患者行静脉血细菌培养与鉴定,同时进行军团菌、支原体、衣原体抗体检测。结果 73例患者中,肺炎链球菌痰培养阳性率为2.74%(2/73),血培养阳性率为1.37%(1/73),尿肺炎链球菌抗原阳性率为15.07%(11/73)。支原体抗体阳性21例(28.77%),衣原体抗体阳性4例(5.48%)。未检出军团菌阳性病例。结论尿抗原测定方法用于诊断肺炎链球菌的阳性率明显提高,对社区获得性肺炎的快速诊断具有良好的应用前景。沈阳地区社区获得性肺炎中支原体感染占主要地位,其次为肺炎链球菌。
Objective To evaluate the clinical significance of urinary antigen detection for rapid diagnosis in patients with community - acquired pneumonia and to know the pathogenic characteristics in our hospital. Methods Totally 73 adult patients with community - acquired pneumonia were enrolled from November 2009 to March 2010 in our hospital. Pneumococcal and Legionella pneumophila C - polysaccharide antigen were detected by using the Binax immmunochromatographic test （ ICT）, and bacteria culture of sputum was conducted. Antibodies of Legionella pneumophila, Mycoplasma and Chlamydia were also detected and bacterial culture of venous blood for the inpatients. Results Among the 73 patients, the positivity rate of sputum culture was 2.74% （2/73）, the rate of blood culture was 1.37% （ 1/73 ）, the rate of Pneumoeoccal positivity in urine ICT was 15.07% （11/73）, Mycoplasma was positive in 21 patients （28.77%）, Chlamydia was positive in 4 patients （5.48%）. Conclusion Urinary antigen detection can obviously raise the positivity rate for diagnosis of pneumococcal pneumonia. It is of good practical future for a rapid diagnosis of community - acquired pneumonia. Mycoplasma infection accounted for the most incidence in community-acquired pneumonia and pneumococcal pneumonia for the next in Shenyang Region.
出处
《中国全科医学》
CAS
CSCD
北大核心
2011年第1期45-48,共4页
Chinese General Practice
关键词
社区获得性肺炎
尿抗原测定
肺炎链球菌
支原体
Community -acquired pneumonia
Urinary antigen detection
Streptococcus pneumoniae
Mycoplasma
