摘要
目的:研究选取了中医辨证为痰浊阻遏及脾肾阳虚证的高脂血症患者作为临床研究对象,探讨穴位埋线疗法对高脂血症痰浊阻遏及脾肾阳虚证的临床疗效。方法:研究选取了中医辨证为痰浊阻遏及脾肾阳虚证的高脂血症患者作为临床研究对象,按照纳入标准和排除标准,将患者60例随机分为埋线组和药物组两组,各30例。埋线组选用足三里、三阴交、丰隆穴、内关、脾俞和胃俞等穴位,每2周埋线1次,每2周为1个疗程,共治疗3个疗程(6周);药物组服用血脂康,每次2粒,每日2次,连服6周。治疗前后分别检测患者血清总胆固醇(TC)、总甘油三酯(TG)、血高密度脂蛋白胆固醇(HDL-C)、血低密度脂蛋白胆固醇(LDL-C)4项血脂水平,并参照2002年国家药品监督管理局《中药新药临床研究指导原则》制定分级计分方法对患者治疗前后进行中医症状分级计分。结果:(1)血脂疗效评定结果显示,经6周治疗后,埋线组与药物组都有较好的疗效,但两组患者改善血脂指标的总有效率无显著性差异(P>0.05)。(2)埋线组血脂疗效与中医证型的关系分析显示,埋线组痰浊阻遏证总有效率明显优于脾肾阳虚证,两证型总有效率比较有显著性差异(P<0.05)。(3)中医症状总疗效判定结果显示,埋线组疗效令人满意,明显优于药物组,两组总有效率比较有显著性差异(P<0.05)。(4)埋线组与药物组治疗前后血脂水平比较显示,治疗前后自身比较,两组血清TC、埋线组血清TG水平明显下降,均有非常显著性差异(P<0.01),两组血清LDL-C含量与治疗前比较也显著下降(P<0.05)。治疗后埋线组与药物组中血清TC、TG、HDL-C、LDL-C含量比较,均无显著性差异(P>0.05)。结论:穴位埋线治疗高脂血症具有显著的临床疗效,在中医症状改善、持续穴位刺激、就诊次数少等方面体现了其治疗优势,值得临床推广应用。
Objective：This clinical study selected those with hyperlipemia of obstruction with tubid phlegm and yang deficiency of spleen and kidney as the subjects,whose curative effect of catgut embedding is to be explored in this study. Methods：The clinical study selected 60 cases with hyperlipemia of obstruction with tubid phlegm and yang deficiency of spleen and kidney as the subjects,who were randomized into two groups according to the internalization standard and exclusion standard,i. e catgut embedding group and medication group,30 cases in each group. The catgut embedding group were treated with catgut embedding once every 2 weeks as a course of treatment,and its treatment lasted 6 weeks. The medication group were given medication of Xuezhikang Capsule,2 pills every time and twice every day for continually 6 weeks. Indexes of blood lipids and TCM symptomatic scores were detected before and after treatment in the two groups. Results：（1） The assessment of curative effect in blood lipids showed that both the catgut embedding group and medication group had gained satisfactory therapeutic effect,whose total effective rates in the improvement of blood-lipid levels indicated no significant difference（P 0. 05） . （2） The analysis of the relationship of curative effect in blood lipids of catgut embedding group and their CM syndromes revealed that the total effective rate of obstruction with tubid phlegm was much higher than that of yang deficiency of spleen and kidney with significant difference（P 0. 05） . （3） The evaluation of total effective rate in CM symptoms carried out after treatment in each group proved satisfactory effect in the catgut embedding group,which demonstrated marked difference in the comparison with the medication group. （4） The result of blood-lipid measurement before and after treatment in each group demonstrated dramatic drop in the serum content of TC and TG,which showed highly sighnificant differences（P 0. 01） ,and the serum content of LDL-C also decreased obviously before and after treatment in each group（P 0. 05） . However,the comparison between the catgut embedding group and medication group after treatment didn＇t show any marked difference in the serum content of TC、TG、HDL-C、LDL-C（P 0. 05） . Conclusion：The catgut embedding therapy has remarkable clinical curative effect,and its advantages are demonstrated in the improvement of CM symptoms,persistent stimulation in acupoints,fewer doctor visits. For all these positive aspects,the catgut embedding therapy deserves more clinical application.
出处
《辽宁中医杂志》
CAS
北大核心
2011年第1期142-146,共5页
Liaoning Journal of Traditional Chinese Medicine
关键词
高脂血症
穴位埋线
针刺
临床研究
hyperlipemia
catgut embedding therapy
acupuncture
clinical study
