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肾衰91冲剂对不同慢性肾衰大鼠毒素作用的实验研究 被引量:4

Experiment study of the effect of Shengshuai 91 chongji (SS91CJ) on toxins of different Chronic renal failure (CRF) rats
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摘要 目的探讨肾衰91冲剂对不同慢性肾衰大鼠毒素作用的机理。方法采用肾衰91冲剂治疗0.75%腺嘌呤和plat法诱发慢性肾衰。结果与模型组相比,肾衰91冲剂组血尿素氮、肌酐、中分子物质、甲基胍、胍基琥珀酸、磷显著降低,钙升高,两组上述各项指标均有显著性差异(P<0.05~0.01)。结论肾衰91冲剂组有降低尿毒证毒素,调整钙磷代谢紊乱的作用。 Objective: To explore the therapeutical mechanism of Shengshuai 91 chongji(SS91CJ) on toxins of different Chronic renal failure (CRF) rats. Methods: SS91CJ was taken to treat the CRF rats which were induced by adenine and platt. Results: BUN,Cr,MMS,MG,GSA and Phosphorus in SS91CJ group were decreased significantly and Calcium was increased,compared with control group,The difference of abovementioned indexes was significant (P<0.050.01) between SS91 CJ and control group. Conclusion:ZSS91CJ has the effect of reducing uremic toxins and regulating calcium and phophorus metabolic disorder.
机构地区 上海中医药大学
出处 《中国中医基础医学杂志》 CAS CSCD 1999年第9期25-28,共4页 JOURNAL OF BASIC CHINESE MEDICINE
关键词 肾衰91冲剂 毒素 肾功能衰竭 SS91CJ uremictoxins calcium phophorus HT
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