摘要
目的探讨肾衰91冲剂对不同慢性肾衰大鼠毒素作用的机理。方法采用肾衰91冲剂治疗0.75%腺嘌呤和plat法诱发慢性肾衰。结果与模型组相比,肾衰91冲剂组血尿素氮、肌酐、中分子物质、甲基胍、胍基琥珀酸、磷显著降低,钙升高,两组上述各项指标均有显著性差异(P<0.05~0.01)。结论肾衰91冲剂组有降低尿毒证毒素,调整钙磷代谢紊乱的作用。
Objective: To explore the therapeutical mechanism of Shengshuai 91 chongji(SS91CJ) on toxins of different Chronic renal failure (CRF) rats. Methods: SS91CJ was taken to treat the CRF rats which were induced by adenine and platt. Results: BUN,Cr,MMS,MG,GSA and Phosphorus in SS91CJ group were decreased significantly and Calcium was increased,compared with control group,The difference of abovementioned indexes was significant (P<0.050.01) between SS91 CJ and control group. Conclusion:ZSS91CJ has the effect of reducing uremic toxins and regulating calcium and phophorus metabolic disorder.
出处
《中国中医基础医学杂志》
CAS
CSCD
1999年第9期25-28,共4页
JOURNAL OF BASIC CHINESE MEDICINE