摘要
目的调查非淋病性尿道炎患者解脲脲支原体(Uu)感染及耐药性,为临床医师合理用药提供科学的试验依据。方法采用法国生物梅里埃公司Mycoplasma IST2支原体试剂盒对2478例非淋病性尿道炎患者进行Uu培养和药敏试验。结果 Uu检测阳性率55.0%;Uu对喹诺酮类抗菌药物的敏感率最低,环丙沙星5.5%,氧氟沙星26.0%;对普那霉素、多西环素、交沙霉素敏感率很高,分别为100.0%、100.0%、98.0%;对红霉素、四环素、阿奇霉素、克拉霉素敏感率居中,在69.0%～93.0%。结论 Uu在非淋病性尿道炎患者中的感染率很高,其对喹诺酮类抗菌药物产生了严重的耐药性。
OBJECTIVE To investigate the infection status and drug-resistance in Ureaplasma urealyticum（Uu） from patients with non-gonococcal urethritis（NGU）,and to provide the scientific bases for the clinical application of antibiotics.METHODS The Uu cultivation and drug susceptibility tests were performed for 2478 patients with NGU by bioMérieux Mycoplasma IST2 kit.RESULTS The total positive detection rate of Uu was 55.0%.The rates of drug sensitivity to quinolones,such as ciprofloxacin（5.5%） and ofloxacin（26.0%）,were the lowest.The rates of drug sensitivity to pristinamycin（100.0%）,doxycycline（100.0%） and josamycin（98.0%） were higher,but to erythromycin,tetracycline,azithromycin and clarithromycin were between 69.0-93.0%.CONCLUSION There is higher infection rate of Uu in NGU.The drug-resistance of Uu to quinolones are serious.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第2期411-412,共2页
Chinese Journal of Nosocomiology
关键词
非淋病性尿道炎
解脲脲支原体
药敏试验
敏感性
Non-gonococcal urethritis
Ureaplasma urealyticum
Drug susceptibility test
Susceptibility
