摘要
目的:探讨胸腔内注射药物治疗结核性胸膜炎的临床治疗效果。方法:选择我院2008年2月～2010年2月结核性胸膜炎患者60例,将患者随机分为观察组(n=30)和对照组(n=30)。两组患者均给予2SHRZ/4HR抗结核方案治疗,同时给予强的松30 mg顿服,服用2周后,逐渐减量,服用6周后停止服用。两组患者均每次抽出胸腔积液800 ml左右,胸腔积液抽出后,向胸腔内注射药物,对照组患者注入地塞米松10 mg,观察组患者向胸腔注入地塞米松10 mg,同时注入异烟肼0.3 g。结果:观察组显效率与对照组比较,差异有统计学意义(P<0.05);观察组总有效率与对照组比较,差异有统计学意义(P<0.05)。结论:胸腔内注入地塞米松和异烟肼治疗结核性胸膜炎临床效果显著,值得借鉴。
Objective： To explore the clinical efficacy of drugs injected into intrapleural cavity on tuberculous pleurisy. Methods： 60 cases with tuberculous pleurisy were selected and randomly divided into two groups from February 2008 to February 2010 in our hospital, observation group （n=30） and control group （n=30）. The same antituberculous programme was used to two groups, and Prednisone （30 mg） was taken, draught, the dose decreased after two weeks, and stopped after six weeks. About 800 ml pleural effusion was extracted from intrapleural cavity at every turn in two groups, after pleural effusion extracted, the drugs was injected into intrapleural cavity. Dexamethasone （10 mg） was injected into intrapleural cavity in control group; Dexamethasone （10 mg） combined with Isoniazid （0.3 g） was injected into intrapleural cavity in observation group. Results： The obvious effective rate in observation group compared with that in control group, there was statistical difference （P〈0.05）; the total effective rate of observation group compared with that of control group, there was statistical difference （P〈0.05）. Conclusion： Dexamethasone combined with Isoniazid injected into intrapleural cavity on tuberculous pleurisy has significant clinical efficacy, and the therapy should be referenced for doctors.
出处
《中国医药导报》
CAS
2011年第3期68-69,共2页
China Medical Herald
