摘要
目的探讨泌尿系结石患者血清胱抑素C(CysC)含量变化的临床应用价值。方法选择泌尿系结石患者44例为结石组,同期选择43例体检正常者为对照组。使用免疫比浊法测定血清CysC含量,并与血清尿素(Urea)、肌酐(Cr)含量比较,采用SPSS13.0软件进行统计学t检验。结果结石组中男、女性患者血清CysC含量分别为(1.24±0.22)和(1.13±0.27)mg/L,均明显高于对照组,差异有统计学意义(P<0.01),血清CysC与Urea和Cr含量之间呈正相关关系(r=0.445、0.571,P<0.01)。患者中合并肾积水7例,其血清CysC含量大幅度升高,与未伴肾积水组比较差异有统计学意义(P<0.01)。结论血清CysC可反映泌尿系结石患者肾功能的早期损伤。
Objective To study serum cystein C（CysC） concentration changes of urinary stone patients.Methods 44 patients with urinary stone were as the stone group and at the same period 43 cases of normal subjects were selected as the control group.The value of serum CysC was measured by immunoturbidimetric assay and compared with that of serum urea nitrogen（Urea）,creatinine（Cr） content.SPSS13.0 software was used for t test.Results The values of serum cystein C（CysC） in males and females of urinary stone group were（1.24±0.22）mg/L and（1.13±0.27）mg/L,they were obviously higher than those in the healthy control group（P0.01）.Serum CysC showed the positive correlations with urea and Cr levels（r=0.445,0.571,P0.01）.Serum CysC levels of 7 hydronephrosis patients were increased obviously,showing significant difference compared with no hydronephrosis group（P0.01）.Conclusion For the diagnosis of renal damage in early stage,the sensitivity of serum CysC is better.
出处
《检验医学与临床》
CAS
2011年第2期172-173,共2页
Laboratory Medicine and Clinic
