摘要
目的:建立测定清开灵泡腾片中栀子苷含量的方法。方法:采用高效液相色谱法。色谱柱为Agilent C18(150mm×4.6mm,5μm),流动相为乙腈-水(11:89),检测波长为238nm,流速为1.0mL·min-1。结果:栀子苷进样量在0.03012～0.90360μg之间与峰面积积分值呈良好的线性关系(r=0.9999);平均回收率为97.02%,RSD=1.0%(n=6)。结论:本方法简便、准确、分离效果好,可用于清开灵泡腾片的质量控制。
OBJECTIVE：To establish the method for the content determination of geniposide in Qingkailing effervescent tablets.METHODS：HPLC was adopted.The separation was performed on Agilent C18（150 mm×4.6 mm,5μm）column with acetonitrile-water（11：89）as mobile phase.The detection wavelength was set at 238 nm.The flow rate was 1.0 mL·min-1.RESULTS：The linear range of geniposide was 0.030 12-0.903 60μg（r=0.999 9）with an average recovery of 97.02%（RSD=1.0%,n=6）.CONCLUSION：The method is simple,accurate and well-separated for the quality control of Qingkailing effervescent tables.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第3期240-241,共2页
China Pharmacy
基金
<中国药典>2010版(一部)标准研究课题(2H-408-414)
