摘要
目的 研究心理反应对癌症病人的细胞免疫的影响。方法 测定５２例消化道癌症（胃癌、大肠癌）患者的焦虑反应、抑郁反应、ＣＤ３、ＣＤ４、ＣＤ８、ＣＤ４／ＣＤ８比值、ＮＫ细胞。结果 严重抑郁反应的患者的ＣＤ４／ＣＤ８ 比值、ＮＫ细胞、ＴＮＦ显著低于无抑郁反应或轻度抑郁反应的患者，明显焦虑的患者的ＩＬ－２ 低于无焦虑或轻度焦虑的患者。结论 严重心理应激导致消化道癌症患者细胞免疫损害。
Objective In order to study the psychological response effect on the cell immunity in the cancer patients Method The anxiety ,depression,CD3,CD4,CD8,NK ,TNF,IL 2 in 52 patients with stomach and digestive cancer were measured . Results CD4/CD8,NK,TNK reduced in the cancerous patients with the major depression, and IL 2 decreased in the patients with the anxiety. Conclusion The study indicts that the major psychological stress may impact on the cell immunity in the patients with cancer.
出处
《中国行为医学科学》
CSCD
1999年第3期195-196,共2页
Chinese Journal of Behavioral Medical Science
基金
吉林省卫生厅科研项目
