摘要
目的:观测从虚郁毒瘀立法组方对萎缩性胃炎鼠模型胃黏膜病理形态的干预作用。方法:采用乙醇+去氧胆酸钠+氨水+吲哚美辛+饥饱失常综合法复制萎缩性胃炎鼠模型,并用从虚郁毒瘀立法组方低、中、高剂量分别进行干预,从对胃黏膜炎症及萎缩分度、胃黏膜厚度方面的影响观测各剂量组的治疗效果。结果:从虚郁毒瘀立法组方中剂量组可明显改善萎缩性鼠模型胃黏膜的炎症和萎缩程度,以及胃黏膜的厚度。结论:从虚郁毒瘀立法组方治疗萎缩性胃炎疗效可靠。
Objective： To observe intervention of the traditional Chinese drug prescription based on asthenia syndrome,depression syndrome,poison syndrome,static blood syndrome on gastric mucosa histopathology of atrophic gastritis.Methods： Alcohol,deoxysodium cholate,ammonia solution,indometacin and disorder between feeding and fasting were used to build the model of atrophic gastritis,which were treated respectively by the high-dose,mid-dose,low-dos traditional Chinese drug prescription based on asthenia syndrome,depression syndrome,poison syndrome,static blood syndrome,and their therapeutic effects were appreciated by the degree of gastric mucosa inflammation and atrophy,thickness of gastric mucosa.Results： The degree of gastric mucosa inflammation and atrophy,thickness of gastric mucosa became better by means of the model of atrophic gastritis treated by mid-dose of the traditional Chinese drug prescription based on asthenia syndrome,depression syndrome,poison syndrome,static blood syndrome.Conclusions： The therapeutic effect of atrophic gastritis treated by the traditional Chinese drug prescription based on asthenia syndrome,depression syndrome,poison syndrome,static blood syndrome is reliable.
出处
《辽宁中医药大学学报》
CAS
2011年第2期38-40,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
福建省教育厅资助项目(JB09136)
关键词
萎缩性胃炎
中医中药
实验研究
atrophic gastritis
traditional Chinese medicine and drugs
empirical study
