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Ⅰ类抗心律失常药物对心脏的抑制作用

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摘要 心律失常（Arrhythmia）是常见的心血管疾病,药物疗法一直是治疗快速心律失常的主要手段。临床绝大多数的抗心律失常药物均是通过影响心肌电兴奋时程中不同时相的离子通道和离子流,使其电生理特性的兴奋性、传导性等产生变化而起作用,达到治疗快速心律失常的目的,但同时也伴有一定的心脏抑制作用。目前,已有许多临床报道及基础研究对Ⅰ类抗心律失常药物的心脏抑制作用及其机理进行了研究,本文对此进行综述。
作者 段继晖
机构地区 山西焦煤西山煤电集团职工总医院ICU
出处 《华北煤炭医学院学报》 2011年第1期35-37,共3页 Journal of North China Coal Medical College
关键词 Ⅰ类抗心律失常药物 心功能 负性肌力
分类号 R961 [医药卫生—药理学]
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参考文献22

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二级参考文献10

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华北煤炭医学院学报
2011年 第1期

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