期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

多囊卵巢综合征与子宫内膜葡萄糖转运蛋白4及血清视黄醇结合蛋白4 被引量：1

下载PDF
导出
摘要 多囊卵巢综合征（（polycystic ovary syndrome,PCOS）是青春期少女和育龄期妇女最常见的妇科内分泌疾病之一,在育龄妇女中发病率约5%～10%[1],是与胰岛素抵抗（IR）存在密切关系的临床综合征。葡萄糖转运蛋白4（GLUT4）及视黄醇结合蛋白4（RBP4）均发现与IR密切相关。本文就PCOS与子宫内膜GLUT4、血清RBP4关系的研究现状做一综述。
作者 张惠娟 樊桂玲 易建平
机构地区 河北联合大学附属唐山市妇幼保健院
出处 《华北煤炭医学院学报》 2011年第1期42-43,共2页 Journal of North China Coal Medical College
关键词 多囊卵巢综合征 胰岛素抵抗 视黄醇结合蛋白4 葡萄糖转运蛋白4
分类号 R711.75 [医药卫生—妇产科学]
  • 相关文献

参考文献16

  • 1Bryant N, Govers R, James D, et al. Regulated Transport Of The Glucose Transporter GLUT4[J]. Nat Rev Mol Cell Biol,2002,3(4) :267.
  • 2Paula CP, Alessandra MV, Jos S, et al. GLUT4 protein is differently modulated during development of obesity in monosodium glutamate - treated mice[ J]. Life Sciences,2002,71 : 1917.
  • 3Carey AL, Lamont B, Andrikopoulos S, et at. Interleukin -6 gene ex- pression is increased in insulin - resistant rat skeletal muscle following insulin stimulation[ J]. Biochemical and Biophysical Research Commu- nications, 2003,302 : 837.
  • 4Watson RT, Pessin J. Intracellular organization of insulin signaling and GLUT4 translocation[ J]. Recent Prog Horm Res,2001,56 : 175.
  • 5Shepherd PR, Kahn BB. Glucose transporters and insulin action -im- plications for insulin resistance and diabetes mellitus [ J ]. N Engl J Med, 1999,341:248.
  • 6王玮,蔡建辉,马毓梅,徐素欣,郝桂敏,李晓冬.GLUT4在多囊卵巢综合征大鼠子宫内膜中的表达及意义[J].中国病理生理杂志,2007,23(3):587-590. 被引量：9
  • 7Mioni R , Chiarelli S , xaminN, et al. Evidence for the presence of glucose Transporter 4 in the endometrium and its regulation in polycystic ovary syndrome patients[ J]. J Clin Endoerinol Metab ,2004,89:4089.
  • 8林仙华,叶碧绿,徐炳森,赵军招,林金菊,杨海燕.二甲双胍对多囊卵巢综合征患者子宫内膜葡萄糖转运蛋白4表达的影响[J].中华妇产科杂志,2008,43(1):63-65. 被引量：6
  • 9Newcomer ME, Ong DE. P1 asma retinol binding Protein: structure and function of the prototypic lipocalin [ J ]. Biochim BioPhys Acta, 2000, 1482 : 57.
  • 10梁学颖,徐琪寿.视黄醇结合蛋白的分子生物学[J].生理科学进展,2000,31(3):277-279. 被引量：31

二级参考文献22

  • 1Kershaw EE ,Flier JS. Adipose tissue as an endocrine organ[ J]. J Clin Endocrinol Metab ,2004,89:2548 - 2556.
  • 2Yang O, Grahom TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes [ J ]. Nature,2005,436 (7049) :356 - 362.
  • 3Timothy EG,Qin Y,Matthias B. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects [ J ]. New Eng J Med,2006 ,354 :2552 - 2563.
  • 4Kotani K, Kim YB, Peroni O, et al. Rosiglitazone treatment normalizes glucose tolerance in adipose-specific GLUT4 knockout mice but renders muscle-specific GLUT4 knockout more diabetic [ abstract ] [ J ]. Diabetes,2001,50 : A274.
  • 5Koistinen HA. Dyslipidemia and a reversible decrease in insulin sensitivity induced by therapy with 13-cis-retinoic acid [ J ]. Diabetes Metab Res Rev,2001,17 :391 - 395.
  • 6Rodondi N. High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne:a pharmaeogenetic study [ J]. Ann Intern Med ,2002,136,582 - 589.
  • 7Fernandez -Veledo S,Hernandez R,Teruel T,et al.Ceramide mediates TNF-alpha-induced insulin resistance on GLUT4 gene expression in brown adipocytes[J].Arch Physiol Biochem,2006,112 (1):13-22.
  • 8Poretsky L,Clemons J,Bogovich K.Hyperinsulinemia and human chorionic gonadotropin synergistically promote the growth of ovarian follicular cysts in rats[J].Metabolism,1992,41(8):903 -910.
  • 9Sheet EE,Tsibris JC,Cook NI,et al.In vitro binding of insulin and epidermal growth factor to human endometrium and endocervix[J].Am J Obstet Gynecol,1985,153(1):60 -65.
  • 10Tan S,Hahn S,Janssen OE.Insulin resistance syndrome and polycystic ovary syndrome:implications for diagnosis and treatment[J].Panminerva Med,2005,47(4):211-217.

共引文献45

同被引文献13

引证文献1

二级引证文献4

华北煤炭医学院学报
2011年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部