氯吡格雷联合阿司匹林治疗老年人ST段抬高型急性心肌梗死疗效观察被引量：33

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摘要目的观察常规溶栓联合氯吡格雷治疗对>70岁的ST段抬高型急性心肌梗死(AMI)患者近期心脏事件的影响。方法收集177例患者分为常规治疗组(87例)和氯吡格雷组(90例),2组均根据体重进行个体化静脉溶栓治疗。常规治疗组单用阿司匹林抗血小板治疗,氯吡格雷组在常规治疗的基础上每日口服氯吡格雷75mg,连用28d。观察并记录住院期间发生的梗死后心绞痛、再发心肌梗死、死亡及复合终点,同时观察出血并发症发生情况。结果 28d后氯吡格雷组复合终点与常规治疗组比较差异有统计学意义(P<0.05),而主要的不良反应2组间比较差异无统计学意义(P>0.05)。结论对于>70岁老年人ST-AMI患者在常规溶栓治疗基础上加用氯吡格雷75mg/d,可显著降低住院期间的病死率和心血管事件发生率。

作者吴立梅王晓凤金学红刘亚丽骆琪芳

机构地区河北省秦皇岛市工人医院心内科

出处《河北医药》 CAS 2010年第23期3298-3299,共2页 Hebei Medical Journal

关键词老年人急性心肌梗死氯吡格雷

分类号 R542.22 [医药卫生—心血管疾病]

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